About   Help   FAQ
Cog6 Gene Detail
Summary
  • Symbol
    Cog6
  • Name
    component of oligomeric golgi complex 6
  • Synonyms
    mKIAA1134
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914792
    NCBI Gene: 67542
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr3:52981875-53017237 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35363 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 24.10 cM, cytoband D
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    COG6, component of oligomeric golgi complex 6
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COG6, component of oligomeric golgi complex 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDG2L, COD2, SHNS
  • Links
    NCBI Gene ID: 57511
    neXtProt AC: NX_Q9Y2V7
    UniProt: Q9Y2V7

  • Chr Location
    13q14.11; chr13:39655627-39791665 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10802
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COG6
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human COG6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    33 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000051735 VEGA Gene Model | MGI Sequence Detail 35363 C57BL/6J ±  kb
    transcript OTTMUST00000130424 VEGA | MGI Sequence Detail 3182 Not Applicable  
    polypeptide OTTMUSP00000069890 VEGA | MGI Sequence Detail 657 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      382 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR010490 Conserved oligomeric Golgi complex subunit 6
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2139872
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory