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Atg12 Gene Detail
Summary
  • Symbol
    Atg12
  • Name
    autophagy related 12
  • Synonyms
    4931423H11Rik, A330058M13Rik, Apg12l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914776
    NCBI Gene: 67526
  • Gene Overview
    MyGene.info: ATG12
Location & Maps
more
  • Sequence Map
    Chr18:46732417-46741579 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9163 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ATG12, autophagy related 12
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATG12, autophagy related 12
    Orthology source: HGNC, HomoloGene
  • Synonyms
    APG12, APG12L, FBR93, HAPG12
  • Links
    NCBI Gene ID: 9140
    neXtProt AC: NX_O94817

  • Chr Location
    5q21-q22; chr5:115828196-115841851 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    2
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032905 Ensembl Gene Model | MGI Sequence Detail 9163 C57BL/6J ±  kb
transcript ENSMUST00000035648 Ensembl | MGI Sequence Detail 2492 Not Applicable  
polypeptide ENSMUSP00000038489 Ensembl | MGI Sequence Detail 141 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004408 ubiquitin-like protein ATG12
  • InterPro Domains
    IPR007242 Ubiquitin-like protein Atg12
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
less
  • All nucleic 132
    cDNA 132

    Microarray probesets 4
Other
Accession IDs
less
MGI:2443723
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 10
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:203690 Martinez-Lopez N, et al., Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Sep;14(9):795-803

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory