About   Help   FAQ
Dennd4c Gene Detail
Summary
  • Symbol
    Dennd4c
  • Name
    DENN/MADD domain containing 4C
  • Synonyms
    1700065A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914769
    NCBI Gene: 329877
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:86748555-86850603 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 40.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914769
protein coding gene Chr4:86748398-86850603 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028414
protein coding gene Chr4:86526995-86629252 (+)
A/J MGP_AJ_G0028375
protein coding gene Chr4:83558333-83659185 (+)
AKR/J MGP_AKRJ_G0028324
protein coding gene Chr4:85621192-85725755 (+)
BALB/cJ MGP_BALBcJ_G0028395
protein coding gene Chr4:83738781-83836659 (+)
C3H/HeJ MGP_C3HHeJ_G0028110
protein coding gene Chr4:86297529-86399277 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028834
protein coding gene Chr4:89832598-89967080 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026134
protein coding gene Chr4:79598706-79693949 (+)
CAST/EiJ MGP_CASTEiJ_G0027551
protein coding gene Chr4:84159090-84261469 (+)
CBA/J MGP_CBAJ_G0028079
protein coding gene Chr4:92602802-92707852 (+)
DBA/2J MGP_DBA2J_G0028228
protein coding gene Chr4:83279659-83395049 (+)
FVB/NJ MGP_FVBNJ_G0028194
protein coding gene Chr4:82265852-82372004 (+)
LP/J MGP_LPJ_G0028328
protein coding gene Chr4:86865689-86974438 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028223
protein coding gene Chr4:97660216-97767781 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028871
protein coding gene Chr4:85697062-85812829 (+)
PWK/PhJ MGP_PWKPhJ_G0027274
protein coding gene Chr4:81603971-81710814 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027099
protein coding gene Chr4:83245909-83347472 (+)
WSB/EiJ MGP_WSBEiJ_G0027627
protein coding gene Chr4:85906417-86016875 (+)



Homology
more
  • Human Ortholog
    DENND4C, DENN domain containing 4C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DENND4C, DENN domain containing 4C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA513M16.3, C9orf55, C9orf55B, RAB10GEF
  • Links
    NCBI Gene ID: 55667
    neXtProt AC: NX_Q5VZ89
    UniProt: Q5VZ89

  • Chr Location
    9p22.1; chr9:19230765-19374268 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038024 Ensembl Gene Model | MGI Sequence Detail 102049 C57BL/6J ±  kb
transcript ENSMUST00000082026 Ensembl | MGI Sequence Detail 7940 Not Applicable  
polypeptide ENSMUSP00000080685 Ensembl | MGI Sequence Detail 1955 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140156
References
more
  • Summaries
    All 40
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory