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Kcnv1
Gene Detail
 Symbol
Name
ID
Kcnv1
potassium channel, subfamily V, member 1
MGI:1914748
Synonyms 2700023A03Rik
Feature Type protein coding gene
Genetic Map
Chromosome 15
17.25 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:45106284-45114934 bp, - strand
From NCBI annotation of GRCm38

  8651 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22811  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcnv1

Human
homologs
Human Homolog KCNV1, potassium channel, subfamily V, member 1
NCBI Gene ID 27012
neXtProt AC  NX_Q6PIU1
Human Synonyms  HNKA, KCNB3, KV2.3, KV8.1
Human Chr (Location)  8q23.2; chr8:109967004-109975734 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Chemically induced (ENU)(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
At weaning, homozygous mutant mice exhibit tetany, tremors and ataxia.
 
Interactions
Kcnv1 interacts with 339 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000022342 (Evidence)
Entrez Gene67498 (Evidence)
UniGene300079
DFCITC1584010, TC1658789
DoTSDT.40170178, DT.91588620, DT.97365265
NIA Mouse Gene IndexU036144
Consensus CDS ProjectCCDS27459.1
International Mouse Knockout Project StatusKcnv1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 67498 NCBI Gene Model | MGI Sequence Detail 8651 C57BL/6J ±  kb
transcript NM_026200 RefSeq | MGI Sequence Detail 4496 C57BL/6 
polypeptide Q8BZN2 UniProt | EBI | MGI Sequence Detail 503 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003970 Potassium channel, voltage dependent, Kv8
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000725 voltage-gated potassium channel KCNV1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:3584402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory