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Kcnv1
Gene Detail
Symbol

Name
ID
Kcnv1
potassium channel, subfamily V, member 1
MGI:1914748
Synonyms
2700023A03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
17.25 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:45106284-45114934 bp, - strand
From Ensembl annotation of GRCm38

  8651 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22811  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNV1
Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcnv1

Human
homologs
KCNV1, potassium channel, voltage gated modifier subfamily V, member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 27012
neXtProt AC: NX_Q6PIU1

Human Synonyms: HNKA, KCNB3, KV2.3, KV8.1

Human Chr (Location): 8q23.2; chr8:109963636-109975734 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Chemically induced (ENU)(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
At weaning, homozygous mutant mice exhibit tetany, tremors and ataxia.
 
Interactions
Kcnv1 interacts with 339 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
cDNA source data(11)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase kcnv1    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000022342 (Evidence)
Entrez Gene 67498 (Evidence)
UniGene 300079
DFCI TC1584010, TC1658789
DoTS DT.40170178, DT.91588620, DT.97365265
NIA Mouse Gene Index U036144
Consensus CDS Project CCDS27459.1
International Mouse Phenotyping Consortium Status Kcnv1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022342 Ensembl Gene Model | MGI Sequence Detail 8651 C57BL/6J ±  kb
transcript ENSMUST00000022967 Ensembl | MGI Sequence Detail 4496 Not Applicable 
polypeptide ENSMUSP00000022967 Ensembl | MGI Sequence Detail 503 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000210 BTB/POZ domain
InterPro IPR005821 Ion transport domain
InterPro IPR003091 Potassium channel
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003970 Potassium channel, voltage dependent, Kv8.1
InterPro IPR011333 POZ domain
InterPro IPR027359 Voltage-dependent channel, four helix bundle domain
InterPro IPR028325 Voltage-gated potassium channel
Protein Ontology PR:000000725 voltage-gated potassium channel KCNV1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:3584402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory