About   Help   FAQ
Kcnv1 Gene Detail
Summary
  • Symbol
    Kcnv1
  • Name
    potassium channel, subfamily V, member 1
  • Synonyms
    2700023A03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914748
    NCBI Gene: 67498
  • Gene Overview
    MyGene.info: KCNV1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:45106284-45114920 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 17.25 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914748
protein coding gene Chr15:45096086-45116490 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021834
protein coding gene Chr15:43728967-43737604 (-)
A/J MGP_AJ_G0021794
protein coding gene Chr15:42071830-42080473 (-)
AKR/J MGP_AKRJ_G0021775
protein coding gene Chr15:43304926-43313549 (-)
BALB/cJ MGP_BALBcJ_G0021801
protein coding gene Chr15:42145865-42154972 (-)
C3H/HeJ MGP_C3HHeJ_G0021575
protein coding gene Chr15:43226071-43234694 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022240
protein coding gene Chr15:45422423-45425667 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019777
protein coding gene Chr15:39569157-39577922 (-)
CAST/EiJ MGP_CASTEiJ_G0021092
protein coding gene Chr15:43727595-43737596 (-)
CBA/J MGP_CBAJ_G0021544
protein coding gene Chr15:46984631-46993259 (-)
DBA/2J MGP_DBA2J_G0021668
protein coding gene Chr15:41877940-41886576 (-)
FVB/NJ MGP_FVBNJ_G0021646
protein coding gene Chr15:41166933-41175568 (-)
LP/J MGP_LPJ_G0021738
protein coding gene Chr15:43513003-43521695 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021670
protein coding gene Chr15:50431454-50439583 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022263
protein coding gene Chr15:43507586-43516208 (-)
PWK/PhJ MGP_PWKPhJ_G0020837
protein coding gene Chr15:41918811-41927468 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020674
protein coding gene Chr15:43167644-43176243 (-)
WSB/EiJ MGP_WSBEiJ_G0021147
protein coding gene Chr15:43401017-43410577 (-)



Homology
more
  • Human Ortholog
    KCNV1, potassium voltage-gated channel modifier subfamily V member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCNV1, potassium voltage-gated channel modifier subfamily V member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HNKA, KCNB3, KV2.3, KV8.1
  • Links
    NCBI Gene ID: 27012
    neXtProt AC: NX_Q6PIU1
    UniProt: Q6PIU1

  • Chr Location
    8q23.2; chr8:109963645-109975847 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Kcnv1
  • Incidental Mutations
  • Find Mice (IMSR)
At weaning, homozygous mutant mice exhibit tetany, tremors and ataxia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022342 Ensembl Gene Model | MGI Sequence Detail 8637 C57BL/6J ±  kb
transcript ENSMUST00000022967 Ensembl | MGI Sequence Detail 4389 Not Applicable  
polypeptide ENSMUSP00000022967 Ensembl | MGI Sequence Detail 503 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
less
MGI:3584402
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory