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Kcnv1 Gene Detail
Summary
  • Symbol
    Kcnv1
  • Name
    potassium channel, subfamily V, member 1
  • Synonyms
    2700023A03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914748
    NCBI Gene: 67498
Location & Maps
more
  • Sequence Map
    Chr15:45106284-45114934 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8651 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    KCNV1, potassium channel, voltage gated modifier subfamily V, member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCNV1, potassium channel, voltage gated modifier subfamily V, member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HNKA, KCNB3, KV2.3, KV8.1
  • Links
    NCBI Gene ID: 27012
    neXtProt AC: NX_Q6PIU1

  • Chr Location
    8q23.2; chr8:109963636-109975734 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Kcnv1
  • Incidental Mutations
At weaning, homozygous mutant mice exhibit tetany, tremors and ataxia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022342 Ensembl Gene Model | MGI Sequence Detail 8651 C57BL/6J ±  kb
transcript ENSMUST00000022967 Ensembl | MGI Sequence Detail 4496 Not Applicable  
polypeptide ENSMUSP00000022967 Ensembl | MGI Sequence Detail 503 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    109 from dbSNP Build 137
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000000725 voltage-gated potassium channel KCNV1
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR005821 Ion transport domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR003968 Potassium channel, voltage dependent, Kv
    IPR003970 Potassium channel, voltage dependent, Kv8.1
    IPR011333 SKP1/BTB/POZ domain
    IPR027359 Voltage-dependent channel, four helix bundle domain
    IPR028325 Voltage-gated potassium channel
Molecular
Reagents
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  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
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MGI:3584402
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory