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Mettl16 Gene Detail
Summary
  • Symbol
    Mettl16
  • Name
    methyltransferase like 16
  • Synonyms
    2610100D03Rik, 2810013M15Rik, A830095F14Rik, Mett10d
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914743
    NCBI Gene: 67493
Location & Maps
more
  • Sequence Map
    Chr11:74770830-74828525 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      57696 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.76 cM, cytoband B4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    METTL16, methyltransferase like 16
  • Vertebrate Orthologs
    9
  • Human Ortholog
    METTL16, methyltransferase like 16
    Orthology source: HGNC, HomoloGene
  • Synonyms
    METT10D
  • Links
    NCBI Gene ID: 79066
    neXtProt AC: NX_Q86W50

  • Chr Location
    17p13.3; chr17:2416049-2511906 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    86
  • Chemically induced (other)
    1
  • Gene trapped
    80
  • Targeted
    5
  • Genomic Mutations
    2 involving Mettl16
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006186 VEGA Gene Model | MGI Sequence Detail 57696 C57BL/6J ±  kb
transcript OTTMUST00000013935 VEGA | MGI Sequence Detail 2073 Not Applicable  
polypeptide OTTMUSP00000006475 VEGA | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    319 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000029627 methyltransferase-like protein 16
  • EC
  • InterPro Domains
    IPR010286 Ribosomal RNA large subunit methyltransferase F-like
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
    IPR017182 S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1924220, MGI:2144287, MGI:2444613
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 19
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory