Alg2
Gene Detail

Symbol Name ID

Alg2 asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) MGI:1914731

Synonyms

1110018A23Rik, 1300013N08Rik, ALPG2, CDGIi

Feature Type

protein coding gene

Genetic Map

Chromosome 4

26.03 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:47465067-47474333 bp, - strand From VEGA annotation of GRCm38   9267 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5930  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Alg2

Human homologs

Human Homolog		ALG2, ALG2, alpha-1,3/1,6-mannosyltransferase
NCBI Gene ID		85365
neXtProt AC		NX_Q9H553
Human Synonyms		CDGIi, hALPG2, NET38
Human Chr (Location)		9q22.33; chr9:101978707-101984246 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ALG2

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	biosynthetic process, dolichol-linked oligosaccharide biosynthetic process, ...
Component	cytoplasm, integral to membrane, ...
Function	alpha-1,3-mannosyltransferase activity, calcium-dependent protein binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (17)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(108)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(108) cDNA(108)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000006801 (Evidence)
Ensembl Gene Model	ENSMUSG00000039740 (Evidence)
Entrez Gene	56737 (Evidence)
UniGene	22218
DFCI	TC1575458
DoTS	DT.491911, DT.97377863
NIA Mouse Gene Index	U025042
EC	2.4.1.132, 2.4.1.257
Consensus CDS Project	CCDS18161.1
International Mouse Knockout Project Status	Alg2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006801	VEGA Gene Model | MGI Sequence Detail	9267	C57BL/6J
transcript	OTTMUST00000015677	VEGA | MGI Sequence Detail	3021	Not Applicable
polypeptide	OTTMUSP00000007208	VEGA | MGI Sequence Detail	415	Not Applicable

All sequences(39) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(45 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR027054	Alpha-1,3/1,6-mannosyltransferase ALG2
InterPro	IPR001296	Glycosyl transferase, family 1
Protein Ontology	PR:000003943	alpha-1,3/1,6-mannosyltransferase ALG2

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All references(33)

Other accession IDs

MGI:1915849