About   Help   FAQ
Cwc25 Gene Detail
Summary
  • Symbol
    Cwc25
  • Name
    CWC25 spliceosome-associated protein
  • Synonyms
    1300013D05Rik, Ccdc49, R75228
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914730
    NCBI Gene: 67480
Location & Maps
more
  • Sequence Map
    Chr11:97745481-97766556 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21076 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 61.09 cM, cytoband D
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CCDC49
  • Links
    NCBI Gene ID: 54883
    neXtProt AC: NX_Q9NXE8

  • Chr Location
    17q12; chr17:38800434-38825350 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 135922
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CWC25
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Genomic Mutations
    1 involving Cwc25
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002750 VEGA Gene Model | MGI Sequence Detail 21076 C57BL/6J ±  kb
transcript OTTMUST00000005462 VEGA | MGI Sequence Detail 3105 Not Applicable  
polypeptide OTTMUSP00000002601 VEGA | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    135 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029372 pre-mRNA-splicing factor CWC25 homolog
  • InterPro Domains
    IPR019339 CBF1-interacting co-repressor CIR, N-terminal domain
    IPR022209 Pre-mRNA splicing factor
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144706, MGI:3035092
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory