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Cwc25 Gene Detail
Summary
  • Symbol
    Cwc25
  • Name
    CWC25 spliceosome-associated protein
  • Synonyms
    1300013D05Rik, Ccdc49, R75228
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914730
    NCBI Gene: 67480
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97745481-97766556 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 61.09 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914730
protein coding gene Chr11:97745470-97766613 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019039
protein coding gene Chr11:100210200-100236207 (-)
A/J MGP_AJ_G0019007
protein coding gene Chr11:96068610-96092797 (-)
AKR/J MGP_AKRJ_G0018977
protein coding gene Chr11:99052670-99073778 (-)
BALB/cJ MGP_BALBcJ_G0018980
protein coding gene Chr11:96569730-96589843 (-)
C3H/HeJ MGP_C3HHeJ_G0018794
protein coding gene Chr11:99176972-99198545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019433
protein coding gene Chr11:103298449-103324990 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017064
protein coding gene Chr11:93526521-93549066 (-)
CAST/EiJ MGP_CASTEiJ_G0018348
protein coding gene Chr11:100038777-100064644 (-)
CBA/J MGP_CBAJ_G0018765
protein coding gene Chr11:107564287-107588483 (-)
DBA/2J MGP_DBA2J_G0018873
protein coding gene Chr11:95619659-95640699 (-)
FVB/NJ MGP_FVBNJ_G0018862
protein coding gene Chr11:95116192-95139998 (-)
LP/J MGP_LPJ_G0018943
protein coding gene Chr11:100712465-100735247 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018889
protein coding gene Chr11:107402601-107425837 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019473
protein coding gene Chr11:99360083-99382417 (-)
PWK/PhJ MGP_PWKPhJ_G0018120
protein coding gene Chr11:96606704-96628628 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017910
protein coding gene Chr11:99074969-99096950 (-)
WSB/EiJ MGP_WSBEiJ_G0018398
protein coding gene Chr11:99260237-99282131 (-)



Homology
more
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC49
  • Links
    NCBI Gene ID: 54883
    neXtProt AC: NX_Q9NXE8
    UniProt: Q9NXE8

  • Chr Location
    17q12; chr17:38800434-38825350 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 135922
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CWC25
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018541 Ensembl Gene Model | MGI Sequence Detail 21076 C57BL/6J ±  kb
transcript ENSMUST00000018685 Ensembl | MGI Sequence Detail 3105 Not Applicable  
polypeptide ENSMUSP00000018685 Ensembl | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144706, MGI:3035092
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory