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Abhd15 Gene Detail
Summary
  • Symbol
    Abhd15
  • Name
    abhydrolase domain containing 15
  • Synonyms
    1300007F04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914727
    NCBI Gene: 67477
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:77515117-77520628 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.63 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914727
protein coding gene Chr11:77515117-77538607 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018750
protein coding gene Chr11:78424792-78450518 (+)
A/J MGP_AJ_G0018716
protein coding gene Chr11:75461267-75484754 (+)
AKR/J MGP_AKRJ_G0018686
protein coding gene Chr11:77751149-77774625 (+)
BALB/cJ MGP_BALBcJ_G0018690
protein coding gene Chr11:75846811-75870304 (+)
C3H/HeJ MGP_C3HHeJ_G0018503
protein coding gene Chr11:77774322-77798341 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019141
protein coding gene Chr11:80885073-80909538 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016776
protein coding gene Chr11:72442779-72466227 (+)
CAST/EiJ MGP_CASTEiJ_G0018057
protein coding gene Chr11:78171931-78197830 (+)
CBA/J MGP_CBAJ_G0018473
protein coding gene Chr11:84400868-84426644 (+)
DBA/2J MGP_DBA2J_G0018582
protein coding gene Chr11:75047839-75071637 (+)
FVB/NJ MGP_FVBNJ_G0018572
protein coding gene Chr11:74618235-74641716 (+)
LP/J MGP_LPJ_G0018653
protein coding gene Chr11:78984334-79007809 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018598
protein coding gene Chr11:84855310-84881925 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019181
protein coding gene Chr11:77960770-77985297 (+)
PWK/PhJ MGP_PWKPhJ_G0017828
protein coding gene Chr11:75805084-75829570 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017619
protein coding gene Chr11:77577194-77600687 (+)
WSB/EiJ MGP_WSBEiJ_G0018110
protein coding gene Chr11:77783366-77810418 (+)



Homology
more
  • Human Ortholog
    ABHD15, abhydrolase domain containing 15
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ABHD15, abhydrolase domain containing 15
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 116236
    neXtProt AC: NX_Q6UXT9
    UniProt: Q6UXT9

  • Chr Location
    17q11.2; chr17:29560661-29567024 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67477 NCBI Gene Model | MGI Sequence Detail 5512 C57BL/6J ±  kb
transcript NM_026185 RefSeq | MGI Sequence Detail 3249 C57BL/6  
polypeptide Q5F2F2 UniProt | EBI | MGI Sequence Detail 459 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:270787 Xia W, et al., Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance. Cell Rep. 2018 May 15;23(7):1948-1961

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory