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Mtfr1
Gene Detail
Symbol

Name
ID
Mtfr1
mitochondrial fission regulator 1
MGI:1914722
Synonyms
1300002C08Rik, 1700080D04Rik, 2810026O10Rik, 4930579E05Rik, Fam54a2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
5.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:19187327-19220817 bp, + strand
From VEGA annotation of GRCm38

  33491 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8763  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MTFR1
Gene Tree: Mtfr1

Human
homologs
MTFR1, mitochondrial fission regulator 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9650
neXtProt AC: NX_Q15390

Human Synonyms: CHPPR, FAM54A2

Human Chr (Location): 8q13.1; chr8:65643873-65771252 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(45) Targeted(2)
Incidental mutations (data from CvDC )
 
Mice homozygous for a gene trapped allele exhibit increased oxidative DNA damage.
 
Interactions
Mtfr1 interacts with 256 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process aerobic respiration, mitochondrial fission
Component cytoplasm, mitochondrion, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (8)    Tissues (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 4
RT-PCR 4
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN mtfr1    NEW 
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000027795 (Evidence)
Ensembl Gene Model ENSMUSG00000027601 (Evidence)
Entrez Gene 67472 (Evidence)
DFCI TC1639811, TC1572459
DoTS DT.101388285, DT.101388284, DT.91357186, DT.101388290, DT.491868, DT.99858538
NIA Mouse Gene Index U003060
Consensus CDS Project CCDS17256.1
International Mouse Phenotyping Consortium Status Mtfr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027795 VEGA Gene Model | MGI Sequence Detail 33491 C57BL/6J ±  kb
transcript OTTMUST00000068780 VEGA | MGI Sequence Detail 1896 Not Applicable 
polypeptide OTTMUSP00000034840 VEGA | MGI Sequence Detail 328 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(11) UniProt(7)
Polymorphisms
SNPs within 2kb(292 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007972 Mitochondrial fission regulator 1
Protein Ontology PR:000010720 mitochondrial fission regulator 1
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)
Other
accession IDs
MGI:1919894, MGI:1923101, MGI:1924244

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory