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Abhd5
Gene Detail
 Symbol
Name
ID
Abhd5
abhydrolase domain containing 5
MGI:1914719
Synonyms 1300003D03Rik, 2010002J10Rik, CGI-58, IECN5, NCIE2
Feature Type protein coding gene
Genetic Map
Chromosome 9
73.03 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:122351608-122381524 bp, + strand
From VEGA annotation of GRCm38

  29917 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41088  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: hypothetical protein YDR125c
Gene Tree: Abhd5

Human
homologs
Human Homolog ABHD5, abhydrolase domain containing 5
NCBI Gene ID 51099
neXtProt AC  NX_Q8WTS1
Human Synonyms  CDS, CGI58, IECN2, NCIE2
Human Chr (Location)  3p21; chr3:43690883-43722725 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ABHD5
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect.
 
Human Diseases Modeled Using Mouse Abhd5 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(5)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cell differentiation, fatty acid metabolic process, ...
Component cytoplasm, cytosol, ...
Function 1-acylglycerol-3-phosphate O-acyltransferase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (65)    Tissues (31)    Images (30)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 65
cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022749 (Evidence)
Ensembl Gene ModelENSMUSG00000032540 (Evidence)
Entrez Gene67469 (Evidence)
NIA Mouse Gene IndexU011178
EC2.3.1.51
Consensus CDS ProjectCCDS23646.1
International Mouse Knockout Project StatusAbhd5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022749 VEGA Gene Model | MGI Sequence Detail 29917 C57BL/6J ±  kb
transcript OTTMUST00000054600 VEGA | MGI Sequence Detail 3157 Not Applicable 
polypeptide OTTMUSP00000026078 VEGA | MGI Sequence Detail 351 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(8) UniProt(5)
Polymorphisms SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000073 Alpha/beta hydrolase fold-1
InterPro IPR002410 Peptidase S33
Protein Ontology PR:000032150 1-acylglycerol-3-phosphate O-acyltransferase ABHD5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:207678 Ohno H, et al., EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex. Nature. 2013 Dec 5;504(7478):163-7
All references(47)
Other
accession IDs
MGI:1917092

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory