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Pdcl
Gene Detail
Symbol

Name
ID
Pdcl
phosducin-like
MGI:1914716
Synonyms
1200011E13Rik, PhLP1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
24.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:37350074-37359332 bp, - strand
From VEGA annotation of GRCm38

  9259 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38043  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PDCL
Protein SuperFamily: phosducin
Gene Tree: Pdcl

Human
homologs
PDCL, phosducin-like
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5082
neXtProt AC: NX_Q13371

Human Synonyms: PhLP

Human Chr (Location): 9q12-q13; chr9:122818097-122828656 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pdcl interacts with 244 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process heterotrimeric G-protein complex assembly, negative regulation of protein refolding, ...
Component cytoplasm
Function protein complex binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(83)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pdcl ; ZFIN pdcl    NEW 
Molecular
reagents
All nucleic(84) cDNA(84)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000012647 (Evidence)
Ensembl Gene Model ENSMUSG00000009030 (Evidence)
Entrez Gene 67466 (Evidence)
UniGene 30709
DFCI TC1574951, TC1592021, TC1689404
DoTS DT.485072, DT.97369768
NIA Mouse Gene Index U022561
Consensus CDS Project CCDS15998.1
International Mouse Phenotyping Consortium Status Pdcl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012647 VEGA Gene Model | MGI Sequence Detail 9259 C57BL/6J ±  kb
transcript OTTMUST00000030098 VEGA | MGI Sequence Detail 2858 Not Applicable 
polypeptide OTTMUSP00000013540 VEGA | MGI Sequence Detail 301 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(28 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001200 Phosducin
InterPro IPR023196 Phosducin N-terminal domain
InterPro IPR024253 Phosducin, thioredoxin-like domain
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000012460 phosducin-like protein
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203537 Gao X, et al., Splice isoforms of phosducin-like protein control the expression of heterotrimeric G proteins. J Biol Chem. 2013 Sep 6;288(36):25760-8
All references(31)
Other
accession IDs
MGI:2139301

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory