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Decr1
Gene Detail
Symbol

Name
ID
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
MGI:1914710
Synonyms
1200012F07Rik, Decr, Nadph
Feature Type
protein coding gene
Genetic Map
Chromosome 4
6.66 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:15917240-15945507 bp, - strand
From VEGA annotation of GRCm38

  28268 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68178  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DECR1
Gene Tree: Decr1

Human
homologs
DECR1, 2,4-dienoyl CoA reductase 1, mitochondrial
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1666
neXtProt AC: NX_Q16698

Human Synonyms: DECR, NADPH, SDR18C1

Human Chr (Location): 8q21.3; chr8:90001352-90052004 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit increased sensitivity to fasting and cold stresses.
 
Interactions
Decr1 interacts with 272 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process fatty acid beta-oxidation, fatty acid metabolic process, ...
Component cytoplasm, extracellular exosome, ...
Function 2,4-dienoyl-CoA reductase (NADPH) activity, NADPH binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (93)    Tissues (93)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 93
cDNA source data(72)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase decr1    NEW 
Molecular
reagents
All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000004641 (Evidence)
Ensembl Gene Model ENSMUSG00000028223 (Evidence)
Entrez Gene 67460 (Evidence)
UniGene 393293
DFCI TC1576471
DoTS DT.533407
NIA Mouse Gene Index U024862
EC 1.3.1.34
Consensus CDS Project CCDS17985.1
International Mouse Phenotyping Consortium Status Decr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004641 VEGA Gene Model | MGI Sequence Detail 28268 C57BL/6J ±  kb
transcript OTTMUST00000010471 VEGA | MGI Sequence Detail 2959 Not Applicable 
polypeptide OTTMUSP00000004962 VEGA | MGI Sequence Detail 335 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(349 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002347 Glucose/ribitol dehydrogenase
InterPro IPR016040 NAD(P)-binding domain
Protein Ontology PR:000006373 2,4-dienoyl-CoA reductase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:174459 Boyle MP, et al., Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory