About   Help   FAQ
Nvl
Gene Detail
Symbol

Name
ID
Nvl
nuclear VCP-like
MGI:1914709
Synonyms
1200009I24Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
84.53 cM, cytoband H4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:181093423-181144157 bp, - strand
From Ensembl annotation of GRCm38

  50735 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: AAA ATPase, Nsf/Cdc48/Vcp types
Gene Tree: Nvl

Human
homologs
Human Homolog NVL, nuclear VCP-like
NCBI Gene ID 4931
neXtProt AC  NX_O15381
Human Chr (Location)  1q41-q42.2; chr1:224227334-224330189 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(24) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Nvl interacts with 80 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component membrane, nucleus
Function ATP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(87)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(87) cDNA(87)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000026516 (Evidence)
Entrez Gene67459 (Evidence)
UniGene263464
NIA Mouse Gene IndexU022149
PDB2RRE
Consensus CDS ProjectCCDS15581.1
International Mouse Knockout Project StatusNvl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026516 Ensembl Gene Model | MGI Sequence Detail 50735 C57BL/6J ±  kb
transcript ENSMUST00000027797 Ensembl | MGI Sequence Detail 3060 Not Applicable 
polypeptide ENSMUSP00000027797 Ensembl | MGI Sequence Detail 855 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(11) UniProt(3)
Polymorphisms
SNPs within 2kb(364 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR003960 ATPase, AAA-type, conserved site
InterPro IPR003959 ATPase, AAA-type, core
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000011534 nuclear valosin-containing protein-like
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/11/2014
MGI 5.20
The Jackson Laboratory