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Nvl Gene Detail
Summary
  • Symbol
    Nvl
  • Name
    nuclear VCP-like
  • Synonyms
    1200009I24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914709
    NCBI Gene: 67459
  • Gene Overview
    MyGene.info: NVL
Location & Maps
more
  • Sequence Map
    Chr1:181087138-181144204 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      57067 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.53 cM, cytoband H4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NVL, nuclear VCP-like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NVL, nuclear VCP-like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NVL2
  • Links
    NCBI Gene ID: 4931
    neXtProt AC: NX_O15381

  • Chr Location
    1q42.11; chr1:224227334-224330201 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    28
  • Chemically induced (other)
    2
  • Gene trapped
    24
  • Targeted
    2
  • Genomic Mutations
    2 involving Nvl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050467 VEGA Gene Model | MGI Sequence Detail 57067 C57BL/6J ±  kb
transcript OTTMUST00000128041 VEGA | MGI Sequence Detail 9392 Not Applicable  
polypeptide OTTMUSP00000068953 VEGA | MGI Sequence Detail 855 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    489 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000011534 nuclear valosin-containing protein-like
  • PDB
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003960 ATPase, AAA-type, conserved site
    IPR003959 ATPase, AAA-type, core
    IPR031996 NVL2, nucleolin binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory