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Slc25a46 Gene Detail
Summary
  • Symbol
    Slc25a46
  • Name
    solute carrier family 25, member 46
  • Synonyms
    1200007B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914703
    NCBI Gene: 67453
Location & Maps
more
  • Sequence Map
    Chr18:31580168-31609902 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29735 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 17.79 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC25A46, solute carrier family 25 member 46
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC25A46, solute carrier family 25 member 46
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HMSN6B
  • Links
    NCBI Gene ID: 91137
    neXtProt AC: NX_Q96AG3

  • Chr Location
    5q22.1; chr5:110738136-110765161 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SLC25A46 associations

Human Disease Mouse Models
       Neuropathy, Hereditary Motor and Sensory, Type Vib; HMSN6B   OMIM: 616505
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    3
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67453 NCBI Gene Model | MGI Sequence Detail 29735 C57BL/6J ±  kb
transcript NM_026165 RefSeq | MGI Sequence Detail 4371 C57BL/6  
polypeptide Q9CQS4 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    161 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029734 solute carrier family 25 member 46
  • InterPro Domains
    IPR023395 Mitochondrial carrier domain
    IPR018108 Mitochondrial substrate/solute carrier
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147212
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory