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Mtpap
Gene Detail
 Symbol
Name
ID
Mtpap
mitochondrial poly(A) polymerase
MGI:1914690
Synonyms 0610027A18Rik, Papd1
Feature Type protein coding gene
Genetic Map
Chromosome 18
2.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:4375592-4397330 bp, + strand
From NCBI annotation of GRCm38

  21739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10008  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mtpap

Human
homologs
Human Homolog MTPAP, mitochondrial poly(A) polymerase
NCBI Gene ID 55149
neXtProt AC  NX_Q9NVV4
Human Synonyms  PAPD1, SPAX4
Human Chr (Location)  10p11.23; chr10:30309801-30349338 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MTPAP
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mtpap interacts with 150 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process histone mRNA catabolic process, mRNA polyadenylation, ...
Component cytoplasm, Golgi apparatus, ...
Function ATP binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (7)    Tissues (1)    Images (7)
Theiler Stages: 23
Assay TypeResults
RNA in situ 7
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(81) cDNA(81)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000024234 (Evidence)
Entrez Gene67440 (Evidence)
UniGene49826
DFCITC1576340, TC1595713, TC1601615, TC1611656
DoTSDT.101401228, DT.110768261, DT.532490, DT.91357254, DT.91367972
NIA Mouse Gene IndexU018356, U323180
EC2.7.7.19
Consensus CDS ProjectCCDS37718.1
International Mouse Knockout Project StatusMtpap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 67440 NCBI Gene Model | MGI Sequence Detail 21739 C57BL/6J ±  kb
transcript NM_026157 RefSeq | MGI Sequence Detail 2651 C57BL/6 
polypeptide Q9D0D3 UniProt | EBI | MGI Sequence Detail 585 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002058 PAP/25A-associated
Protein Ontology PR:000010745 poly(A) RNA polymerase, mitochondrial
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)
Other
accession IDs
MGI:2147373

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory