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Mtpap Gene Detail
Summary
  • Symbol
    Mtpap
  • Name
    mitochondrial poly(A) polymerase
  • Synonyms
    0610027A18Rik, Papd1, Tent6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914690
    NCBI Gene: 67440
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:4375592-4397330 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 2.77 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    62 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914690
protein coding gene Chr18:4375592-4398798 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024123
protein coding gene Chr18:1220857-1243969 (+)
A/J MGP_AJ_G0024085
protein coding gene Chr18:1259635-1281494 (+)
AKR/J MGP_AKRJ_G0024053
protein coding gene Chr18:1242424-1264122 (+)
BALB/cJ MGP_BALBcJ_G0024085
protein coding gene Chr18:1244789-1267297 (+)
C3H/HeJ MGP_C3HHeJ_G0023850
protein coding gene Chr18:1218749-1240487 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024530
protein coding gene Chr18:1356968-1378706 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021969
protein coding gene Chr18:1079935-1098853 (+)
CAST/EiJ MGP_CASTEiJ_G0023329
protein coding gene Chr18:1188189-1212566 (+)
CBA/J MGP_CBAJ_G0023824
protein coding gene Chr18:1315540-1337278 (+)
DBA/2J MGP_DBA2J_G0023952
protein coding gene Chr18:1189015-1210673 (+)
FVB/NJ MGP_FVBNJ_G0023918
protein coding gene Chr18:1176886-1198584 (+)
LP/J MGP_LPJ_G0024036
protein coding gene Chr18:1307872-1329610 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023946
protein coding gene Chr18:1336455-1358193 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024575
protein coding gene Chr18:1193208-1214946 (+)
PWK/PhJ MGP_PWKPhJ_G0023074
protein coding gene Chr18:1191284-1213771 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022885
protein coding gene Chr18:1465641-1487832 (+)
WSB/EiJ MGP_WSBEiJ_G0023395
protein coding gene Chr18:1220066-1241804 (+)



Homology
more
  • Human Ortholog
    MTPAP, mitochondrial poly(A) polymerase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MTPAP, mitochondrial poly(A) polymerase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PAPD1, SPAX4, TENT6
  • Links
    NCBI Gene ID: 55149
    neXtProt AC: NX_Q9NVV4
    UniProt: Q9NVV4

  • Chr Location
    10p11.23; chr10:30309801-30349338 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10008
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MTPAP
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human MTPAP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024234 Ensembl Gene Model | MGI Sequence Detail 21739 C57BL/6J ±  kb
transcript ENSMUST00000025077 Ensembl | MGI Sequence Detail 2651 Not Applicable  
polypeptide ENSMUSP00000025077 Ensembl | MGI Sequence Detail 585 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 82

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147373
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory