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Mtpap
Gene Detail
Symbol

Name
ID
Mtpap
mitochondrial poly(A) polymerase
MGI:1914690
Synonyms
0610027A18Rik, Papd1
Feature Type
protein coding gene
Genetic Map
Chromosome 18
2.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:4375592-4397330 bp, + strand
From Ensembl annotation of GRCm38

  21739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10008  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mtpap

Human
homologs
Human Homolog MTPAP, mitochondrial poly(A) polymerase
NCBI Gene ID 55149
neXtProt AC  NX_Q9NVV4
Human Synonyms  PAPD1, SPAX4
Human Chr (Location)  10p11.23; chr10:30309801-30349338 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MTPAP
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mtpap interacts with 150 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process histone mRNA catabolic process, mRNA polyadenylation, ...
Component cytoplasm, intracellular membrane-bounded organelle, ...
Function ATP binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (7)    Tissues (1)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 7
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(81) cDNA(81)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000024234 (Evidence)
Entrez Gene67440 (Evidence)
UniGene49826
DFCITC1611656, TC1601615, TC1595713, TC1576340
DoTSDT.110768261, DT.101401228, DT.91367972, DT.91357254, DT.532490
NIA Mouse Gene IndexU018356, U323180
EC2.7.7.19
Consensus CDS ProjectCCDS37718.1
International Mouse Knockout Project StatusMtpap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024234 Ensembl Gene Model | MGI Sequence Detail 21739 C57BL/6J ±  kb
transcript ENSMUST00000025077 Ensembl | MGI Sequence Detail 2651 Not Applicable 
polypeptide ENSMUSP00000025077 Ensembl | MGI Sequence Detail 585 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002058 PAP/25A-associated
Protein Ontology PR:000010745 poly(A) RNA polymerase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGI:2147373

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory