Xab2
Gene Detail

Symbol Name ID

Xab2 XPA binding protein 2 MGI:1914689

Synonyms

0610041O14Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 8

1.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:3608421-3621316 bp, - strand From VEGA annotation of GRCm38   12896 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5738  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Xab2

Human homologs

Human Homolog		XAB2, XPA binding protein 2
NCBI Gene ID		56949
neXtProt AC		NX_Q9HCS7
Human Synonyms		HCNP, HCRN, NTC90, SYF1
Human Chr (Location)		19p13.2; chr19:7684411-7694439 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Homozygous null embryos die by the blastocyst stage (E3.5) and some eight-cell stage embryos do not undergo compaction.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	blastocyst development, DNA repair, ...
Component	catalytic step 2 spliceosome, intracellular, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (15)    Tissues (10)    Images (7)
Theiler Stages: 17, 19, 28

Assay Type	Results
RNA in situ	15

cDNA source data(90)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(91) cDNA(91)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000034606 (Evidence)
Ensembl Gene Model	ENSMUSG00000019470 (Evidence)
Entrez Gene	67439 (Evidence)
UniGene	23739
DFCI	TC1573042, TC1614357
NIA Mouse Gene Index	U029537
Consensus CDS Project	CCDS22065.1
International Mouse Knockout Project Status	Xab2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000034606	VEGA Gene Model | MGI Sequence Detail	12896	C57BL/6J
transcript	OTTMUST00000087802	VEGA | MGI Sequence Detail	2677	Not Applicable
polypeptide	OTTMUSP00000047812	VEGA | MGI Sequence Detail	855	Not Applicable

All sequences(49) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(82 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003107	RNA-processing protein, HAT helix
InterPro	IPR011990	Tetratricopeptide-like helical
InterPro	IPR019734	Tetratricopeptide repeat
InterPro	IPR013026	Tetratricopeptide repeat-containing domain
InterPro	IPR013105	Tetratricopeptide TPR2
Protein Ontology	PR:000017470	pre-mRNA-splicing factor SYF1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGI:2142733