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Ssr3 Gene Detail
Summary
  • Symbol
    Ssr3
  • Name
    signal sequence receptor, gamma
  • Synonyms
    0610038P07Rik, translocon-associated protein gamma, Trap-gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914687
    NCBI Gene: 67437
Location & Maps
more
  • Sequence Map
    Chr3:65379655-65392623 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12969 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SSR3, signal sequence receptor subunit 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SSR3, signal sequence receptor subunit 3
    Orthology source: HomoloGene
  • Synonyms
    TRAPG
  • Links
    NCBI Gene ID: 6747
    neXtProt AC: NX_Q9UNL2

  • Chr Location
    3q25.31; chr3:156540140-156555184 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Ssr3
  • Incidental Mutations
    APF
Mice homozygous for a null mutation display neonatal lethality with growth retardation, reduced placental size and impaired placental vascular development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028773 VEGA Gene Model | MGI Sequence Detail 12969 C57BL/6J ±  kb
transcript OTTMUST00000071272 VEGA | MGI Sequence Detail 2957 Not Applicable  
polypeptide OTTMUSP00000036487 VEGA | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015661 translocon-associated protein subunit gamma
  • InterPro Domains
    IPR009779 Translocon-associated protein subunit gamma
Molecular
Reagents
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  • All nucleic 397
    cDNA 397

    Microarray probesets 6
Other
Accession IDs
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MGI:2139852, MGI:2139887, MGI:2140004
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:167832 Yamaguchi YL, et al., Translocon-associated protein subunit Trap-gamma/Ssr3 is required for vascular network formation in the mouse placenta. Dev Dyn. 2011 Feb;240(2):394-403

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory