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Ssr3
Gene Detail
Symbol

Name
ID
Ssr3
signal sequence receptor, gamma
MGI:1914687
Synonyms
0610038P07Rik, translocon-associated protein gamma, Trap-gamma
Feature Type
protein coding gene
Genetic Map
Chromosome 3
30.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:65379655-65392623 bp, - strand
From VEGA annotation of GRCm38

  12969 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5154  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: translocon-associated protein, gamma subunit
Gene Tree: Ssr3

Human
homologs
Human Homolog SSR3, signal sequence receptor, gamma (translocon-associated protein gamma)
NCBI Gene ID 6747
neXtProt AC  NX_Q9UNL2
Human Synonyms  TRAPG
Human Chr (Location)  3q25.31; chr3:156540140-156555184 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(6) Targeted(1)
Incidental mutations (data from APF )
 
Mice homozygous for a null mutation display neonatal lethality with growth retardation, reduced placental size and impaired placental vascular development.
 
Interactions
Ssr3 interacts with 286 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process cotranslational protein targeting to membrane
Component endoplasmic reticulum, integral component of endoplasmic reticulum membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (12)    Tissues (12)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(397)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(397) cDNA(397)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000028773 (Evidence)
Ensembl Gene ModelENSMUSG00000027828 (Evidence)
Entrez Gene67437 (Evidence)
UniGene232728
DFCITC1637702, TC1590761, TC1607661, TC1573191
DoTSDT.111065146, DT.101268684, DT.111065081, DT.101289329, DT.94250550, DT.91289243, DT.94293956, DT.97388824
Consensus CDS ProjectCCDS17386.1
International Mouse Knockout Project StatusSsr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028773 VEGA Gene Model | MGI Sequence Detail 12969 C57BL/6J ±  kb
transcript OTTMUST00000071272 VEGA | MGI Sequence Detail 2957 Not Applicable 
polypeptide OTTMUSP00000036487 VEGA | MGI Sequence Detail 185 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009779 Translocon-associated, gamma subunit
Protein Ontology PR:000015661 translocon-associated protein subunit gamma
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:167832 Yamaguchi YL, et al., Translocon-associated protein subunit Trap-gamma/Ssr3 is required for vascular network formation in the mouse placenta. Dev Dyn. 2011 Feb;240(2):394-403
All references(34)
Other
accession IDs
MGI:2139852, MGI:2139887, MGI:2140004

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory