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Rps20 Gene Detail
Summary
  • Symbol
    Rps20
  • Name
    ribosomal protein S20
  • Synonyms
    4632426K06Rik, Dsk4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914677
    NCBI Gene: 67427
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:3831334-3835600 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 2.14 cM, cytoband A1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914677
 protein coding gene Chr4:3831334-3835665 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028024
 protein coding gene Chr4:320438-325638 (-)
A/J MGP_AJ_G0027982
 protein coding gene Chr4:386609-393761 (-)
AKR/J MGP_AKRJ_G0027948
 protein coding gene Chr4:326832-335109 (-)
BALB/cJ MGP_BALBcJ_G0027994
 protein coding gene Chr4:357356-363463 (-)
C3H/HeJ MGP_C3HHeJ_G0027724
 protein coding gene Chr4:491014-496238 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028437
 protein coding gene Chr4:467430-471761 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025781
 protein coding gene Chr4:321109-325527 (-)
CAST/EiJ MGP_CASTEiJ_G0027177
 protein coding gene Chr4:398936-403285 (-)
CBA/J MGP_CBAJ_G0027699
 protein coding gene Chr4:335889-340240 (-)
DBA/2J MGP_DBA2J_G0027839
 protein coding gene Chr4:357056-361407 (-)
FVB/NJ MGP_FVBNJ_G0027806
 protein coding gene Chr4:289879-294210 (-)
LP/J MGP_LPJ_G0027950
 protein coding gene Chr4:367433-371784 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027839
 protein coding gene Chr4:523306-527637 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028496
 protein coding gene Chr4:325443-329621 (-)
PWK/PhJ MGP_PWKPhJ_G0026899
 protein coding gene Chr4:416642-421204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026729
 protein coding gene Chr4:341864-346219 (-)
WSB/EiJ MGP_WSBEiJ_G0027257
 protein coding gene Chr4:465210-470410 (-)



Homology
more
  • Human Ortholog
    RPS20, ribosomal protein S20
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS20, ribosomal protein S20
  • Synonyms
    S20, uS10
  • Links
    NCBI Gene ID: 6224
    neXtProt AC: NX_P60866
    UniProt: P60866

  • Chr Location
    8q12.1; chr8:56067254-56074510 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 5 genetic backgrounds
    1 phenotype from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygous mutant animals exhibit pigmentation defects affecting the footpads. Homozygous mutant animals are embryonic lethal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    9
  • cDNA Data
    12
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67427 NCBI Gene Model | MGI Sequence Detail 4267 C57BL/6J ±  kb
    transcript NM_026147 RefSeq | MGI Sequence Detail 3641 C57BL/6  
    polypeptide P60867 UniProt | EBI | MGI Sequence Detail 119 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000014264 eukaryotic-type small ribosomal subunit protein uS10
      (term hierarchy)
    • PDB
      7CPU, 7CPV, 7LS1, 7LS2
    • InterPro Domains
      IPR001848 Small ribosomal subunit protein uS10
      IPR018268 Small ribosomal subunit protein uS10, conserved site
      IPR027486 Small ribosomal subunit protein uS10 domain
      IPR036838 Small ribosomal subunit protein uS10 domain superfamily
      IPR005729 Small ribosomal subunit protein uS10, eukaryotic/archaeal
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 14
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2450685
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
    • Latest
      J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory