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Coq8a Gene Detail
Summary
  • Symbol
    Coq8a
  • Name
    coenzyme Q8A
  • Synonyms
    4632432J16Rik, Adck3, Cabc1, mKIAA0451
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914676
    NCBI Gene: 67426
  • Gene Overview
    MyGene.info: COQ8A
Location & Maps
more
  • Sequence Map
    Chr1:180165238-180199602 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34365 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.15 cM, cytoband H4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    COQ8A, coenzyme Q8A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COQ8A, coenzyme Q8A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADCK3, ARCA2, CABC1, COQ10D4, COQ8, SCAR9
  • Links
    NCBI Gene ID: 56997
    neXtProt AC: NX_Q8NI60

  • Chr Location
    1q42.13; chr1:226940237-226987545 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11345
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COQ8A
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human COQ8A associations

Human Disease Mouse Models
       Coenzyme Q10 Deficiency, Primary, 4; COQ10D4   OMIM: 612016
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Coq8a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034709 VEGA Gene Model | MGI Sequence Detail 34365 C57BL/6J ±  kb
transcript OTTMUST00000088142 VEGA | MGI Sequence Detail 4026 Not Applicable  
polypeptide OTTMUSP00000048027 VEGA | MGI Sequence Detail 645 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    456 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138259
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory