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Pdlim7 Gene Detail
Summary
  • Symbol
    Pdlim7
  • Name
    PDZ and LIM domain 7
  • Synonyms
    1110003B01Rik, 2410002J21Rik, Enigma
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914649
    NCBI Gene: 67399
  • Gene Overview
    MyGene.info: PDLIM7
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55497487-55513473 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 30.06 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914649
protein coding gene Chr13:55495795-55513676 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020600
protein coding gene Chr13:54985278-55003193 (-)
A/J MGP_AJ_G0020554
protein coding gene Chr13:52950527-52968468 (-)
AKR/J MGP_AKRJ_G0020532
protein coding gene Chr13:54514782-54532657 (-)
BALB/cJ MGP_BALBcJ_G0020550
protein coding gene Chr13:53182568-53200803 (-)
C3H/HeJ MGP_C3HHeJ_G0020349
protein coding gene Chr13:54327464-54345364 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020984
protein coding gene Chr13:56641458-56660371 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018566
protein coding gene Chr13:50888425-50906468 (-)
CAST/EiJ MGP_CASTEiJ_G0019863
protein coding gene Chr13:54427449-54448262 (-)
CBA/J MGP_CBAJ_G0020309
protein coding gene Chr13:58820332-58838297 (-)
DBA/2J MGP_DBA2J_G0020432
protein coding gene Chr13:52501780-52519647 (-)
FVB/NJ MGP_FVBNJ_G0020411
protein coding gene Chr13:51971955-51990634 (-)
LP/J MGP_LPJ_G0020508
protein coding gene Chr13:55238269-55256087 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020440
protein coding gene Chr13:58284737-58302614 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021027
protein coding gene Chr13:54095374-54114250 (-)
PWK/PhJ MGP_PWKPhJ_G0019619
protein coding gene Chr13:52527815-52546438 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019446
protein coding gene Chr13:53022730-53040695 (-)
WSB/EiJ MGP_WSBEiJ_G0019925
protein coding gene Chr13:54452530-54473163 (-)



Homology
more
  • Human Ortholog
    PDLIM7, PDZ and LIM domain 7
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PDLIM7, PDZ and LIM domain 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LMP1, LMP3
  • Links
    NCBI Gene ID: 9260
    neXtProt AC: NX_Q9NR12
    UniProt: Q9NR12

  • Chr Location
    5q35.3; chr5:177483394-177497605 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 1 allele in 1 genetic background
    4 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit heart defects and hemostatic dysfunction.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67399 NCBI Gene Model | MGI Sequence Detail 15987 C57BL/6J ±  kb
    transcript NM_001114088 RefSeq | MGI Sequence Detail 2626 C57BL/6  
    polypeptide Q3TJD7 UniProt | EBI | MGI Sequence Detail 457 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 99
      cDNA 98
      Primer pair 1

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:1919209, MGI:2145386
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:256956 Brinegar AE, et al., Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Elife. 2017 Aug 11;6

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory