About   Help   FAQ
Srpr Gene Detail
Summary
  • Symbol
    Srpr
  • Name
    signal recognition particle receptor ('docking protein')
  • Synonyms
    1300011P19Rik, D11Mgi27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914648
    NCBI Gene: 67398
Location & Maps
more
  • Sequence Map
    Chr9:35200175-35247973 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      47799 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SRPRA, SRP receptor alpha subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SRPRA, SRP receptor alpha subunit
    Orthology source: HomoloGene
  • Synonyms
    DP, Sralpha, SRPR
  • Links
    NCBI Gene ID: 6734
    neXtProt AC: NX_P08240

  • Chr Location
    11q24.2; chr11:126262919-126268982 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2364
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SRPRA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031587 VEGA Gene Model | MGI Sequence Detail 47799 C57BL/6J ±  kb
transcript OTTMUST00000078230 VEGA | MGI Sequence Detail 2993 Not Applicable  
polypeptide OTTMUSP00000041581 VEGA | MGI Sequence Detail 636 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    199 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015632 signal recognition particle receptor subunit alpha
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR011012 Longin-like domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR007222 Signal recognition particle receptor, alpha subunit, N-terminal
    IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
    IPR013822 Signal recognition particle, SRP54 subunit, helical bundle
Molecular
Reagents
less
  • All nucleic 238
    cDNA 238

    Microarray probesets 5
Other
Accession IDs
less
MGI:2681058
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197701 Lang S, et al., Different effects of Sec61alpha, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci. 2012 Apr 15;125(Pt 8):1958-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory