Cxxc5 Gene Detail

Summary

• Symbol
  Cxxc5
• Name
  CXXC finger 5
• Synonyms
  4930415K17Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1914643
  NCBI Gene: 67393
• Gene Overview
  MyGene.info: CXXC5

Location & Maps

• Sequence Map
  Chr18:35829818-35861687 bp, + strand
• From Ensembl annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    31870 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 19.26 cM, cytoband B3
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  CXXC5, CXXC finger protein 5

• Vertebrate Orthologs
  9

• Human Ortholog
  CXXC5, CXXC finger protein 5
  Orthology source: HomoloGene, HGNC
• Synonyms
  CF5, HSPC195, RINF, WID
• Links
  HGNC:26943

  NCBI Gene ID: 51523

  neXtProt AC: NX_Q7LFL8

  
  
• Chr Location
  5q31.2; chr5:139648716-139683882 (+)  GRCh38.p2

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• HomoloGene
  Vertebrate Homology Class 9517
  1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish
  
• HCOP
  human homology predictions: CXXC5
• Gene Tree
  Cxxc5
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  21 phenotypes from 1 allele in 1 genetic background
  3 images
  14 phenotype references
  

• All Mutations and Alleles
  88
• Gene trapped
  82
• Targeted
  6
• Incidental Mutations
  Mutagenetix , APF

Mice homozygous for a null allele exhibit an increase in bone mass, bone mineral density, osteocyte dendrite formation, and bone formation rate.

Gene Ontology
(GO)
Classifications

• All GO Annotations
  11
• GO References
  3

• External Resources
  FuncBase

Expression

• cDNA Data
  134

• Other Mouse Links
  Allen Institute
  GEO
• Other Vertebrate Links
  GEISHA CXXC5
  ZFIN cxxc5a

Interactions

• Cxxc5 interacts with 210 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  26
• RefSeq
  12
• UniProt
  1
• CCDS
  CCDS29150.1
• UniGene
  94560

• Ensembl
  ENSMUSG00000046668 (Evidence)
• NCBI Gene
  67393

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000046668	Ensembl Gene Model | MGI Sequence Detail	31870	C57BL/6J
transcript	ENSMUST00000060722	Ensembl | MGI Sequence Detail	2271	Not Applicable
polypeptide	ENSMUSP00000054307	Ensembl | MGI Sequence Detail	317	Not Applicable

Polymorphisms

• SNPs within 2kb
  67 from dbSNP Build 142

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000006076 CXXC-type zinc finger protein 5
• InterPro Domains
  IPR002857 Zinc finger, CXXC-type

Molecular
Reagents

• All nucleic 134

  cDNA 134

  
  

  Microarray probesets 4

References

• Summaries
  All 34

  Gene Ontology 3

  Phenotypes 14
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:227338 Kim MY, et al., CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation. Glia. 2015 Oct 14;