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Brd3 Gene Detail
Summary
  • Symbol
    Brd3
  • Name
    bromodomain containing 3
  • Synonyms
    2410084F24Rik, Fsrg2, ORFX, RINGL3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914632
    NCBI Gene: 67382
  • Gene Overview
    MyGene.info: BRD3
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:27445576-27507657 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.38 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914632
protein coding gene Chr2:27445576-27507662 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025514
protein coding gene Chr2:25433630-25501233 (-)
A/J MGP_AJ_G0025491
protein coding gene Chr2:24479302-24543778 (-)
AKR/J MGP_AKRJ_G0025461
protein coding gene Chr2:25273934-25351257 (-)
BALB/cJ MGP_BALBcJ_G0025487
protein coding gene Chr2:24596255-24661231 (-)
C3H/HeJ MGP_C3HHeJ_G0025248
protein coding gene Chr2:25209335-25275256 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025931
protein coding gene Chr2:26289167-26367887 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023342
protein coding gene Chr2:23303664-23362064 (-)
CAST/EiJ MGP_CASTEiJ_G0024711
protein coding gene Chr2:25086653-25153986 (-)
CBA/J MGP_CBAJ_G0025226
protein coding gene Chr2:27206608-27272179 (-)
DBA/2J MGP_DBA2J_G0025359
protein coding gene Chr2:24294927-24358318 (-)
FVB/NJ MGP_FVBNJ_G0025321
protein coding gene Chr2:24058134-24122621 (-)
LP/J MGP_LPJ_G0025445
protein coding gene Chr2:25378359-25444609 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025352
protein coding gene Chr2:27228223-27295729 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025990
protein coding gene Chr2:25204638-25273200 (-)
PWK/PhJ MGP_PWKPhJ_G0024459
protein coding gene Chr2:24090568-24148331 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024259
protein coding gene Chr2:25357186-25431581 (-)
WSB/EiJ MGP_WSBEiJ_G0024780
protein coding gene Chr2:25325875-25395575 (-)



Homology
more
  • Human Ortholog
    BRD3, bromodomain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BRD3, bromodomain containing 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ORFX, RING3L
  • Links
    NCBI Gene ID: 8019
    neXtProt AC: NX_Q15059
    UniProt: Q15059

  • Chr Location
    9q34.2; chr9:134030305-134068533 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 81801
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BRD3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67382 NCBI Gene Model | MGI Sequence Detail 62082 C57BL/6J ±  kb
transcript NM_023336 RefSeq | MGI Sequence Detail 5429 C57BL/6  
polypeptide Q8K2F0 UniProt | EBI | MGI Sequence Detail 726 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 196
    cDNA 194
    Primer pair 2

    Microarray probesets 9
Other
Accession IDs
less
MGI:2139285
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:195583 Zhang J, et al., A newly identified microRNA, mmu-miR-7578, functions as a negative regulator on inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 via targeting Egr1 in vivo. J Biol Chem. 2013 Feb 8;288(6):4310-20

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory