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Qprt
Gene Detail
Symbol

Name
ID
Qprt
quinolinate phosphoribosyltransferase
MGI:1914625
Synonyms
2410027J01Rik, nicotinate-nucleotide pyrophosphorylase, QPRTase
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:127107114-127122226 bp, - strand
From VEGA annotation of GRCm38

  15113 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8623  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Protein SuperFamily: NadC_ModD
Gene Tree: Qprt

Human
homologs
Human Homolog QPRT, quinolinate phosphoribosyltransferase
NCBI Gene ID 23475
neXtProt AC  NX_Q15274
Human Synonyms  HEL-S-90n, QPRTase
Human Chr (Location)  16p11.2; chr16:29679042-29698003 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(5) Targeted(5)
Genomic Mutations involving Qprt (2)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Qprt interacts with 137 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (117)    Tissues (97)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 117
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000029412 (Evidence)
Ensembl Gene ModelENSMUSG00000030674 (Evidence)
Entrez Gene67375 (Evidence)
DFCITC1617286, TC1582476
DoTSDT.111082416, DT.488478, DT.94246595
NIA Mouse Gene IndexU029277
EC2.4.2.19
Consensus CDS ProjectCCDS40138.1
International Mouse Knockout Project StatusQprt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029412 VEGA Gene Model | MGI Sequence Detail 15113 C57BL/6J ±  kb
transcript OTTMUST00000072893 VEGA | MGI Sequence Detail 2050 Not Applicable 
polypeptide OTTMUSP00000037627 VEGA | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(129 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR004393 Nicotinate-nucleotide pyrophosphorylase
InterPro IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD
InterPro IPR002638 Quinolinate phosphoribosyl transferase, C-terminal
InterPro IPR022412 Quinolinate phosphoribosyl transferase, N-terminal
Protein Ontology PR:000013567 nicotinate-nucleotide pyrophosphorylase [carboxylating]
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:2142018

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory