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Qpctl
Gene Detail
 Symbol
Name
ID
Qpctl
glutaminyl-peptide cyclotransferase-like
MGI:1914619
Synonyms 1810019P04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
9.46 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:19140217-19149196 bp, - strand
From NCBI annotation of GRCm38

  8980 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9765  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Gene Tree: Qpctl

Human
homologs
Human Homolog QPCTL, glutaminyl-peptide cyclotransferase-like
NCBI Gene ID 54814
neXtProt AC  NX_Q9NXS2
Human Synonyms  gQC
Human Chr (Location)  19q13.32; chr19:45692483-45703990 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Chemically induced (ENU)(1) Targeted(1)
Interactions
Qpctl interacts with 128 markers (Mir7-1, Mir15a, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
Component Golgi apparatus, integral component of membrane, ...
Function glutaminyl-peptide cyclotransferase activity, metal ion binding, ...
External Resources: FuncBase
Expression
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000030407 (Evidence)
Entrez Gene67369 (Evidence)
DFCITC1580807, TC1651729
NIA Mouse Gene IndexU028215
EC2.3.2.5
Consensus CDS ProjectCCDS20891.1
International Mouse Knockout Project StatusQpctl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 67369 NCBI Gene Model | MGI Sequence Detail 8980 C57BL/6J ±  kb
transcript NM_026111 RefSeq | MGI Sequence Detail 2100 C57BL/6 
polypeptide Q8BH73 UniProt | EBI | MGI Sequence Detail 383 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007484 Peptidase M28
Protein Ontology PR:000013566 glutaminyl-peptide cyclotransferase-like protein
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:176575 Alexandru A, et al., Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated A{beta} Is Induced by Pyroglutamate-A{beta} Formation. J Neurosci. 2011 Sep 7;31(36):12790-12801
All references(29)
Other
accession IDs
MGI:2142285

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory