Qpctl
Gene Detail

Symbol Name ID

Qpctl glutaminyl-peptide cyclotransferase-like MGI:1914619

Synonyms

1810019P04Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 7

9.46 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:19140217-19149196 bp, - strand From NCBI annotation of GRCm38   8980 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9765  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Gene Tree: Qpctl

Human homologs

Human Homolog		QPCTL, glutaminyl-peptide cyclotransferase-like
NCBI Gene ID		54814
neXtProt AC		NX_Q9NXS2
Human Synonyms		gQC
Human Chr (Location)		19q13.32; chr19:46195741-46207248 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(1) Chemically induced(1)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase, proteolysis
Component	Golgi apparatus, integral to membrane, ...
Function	glutaminyl-peptide cyclotransferase activity, metal ion binding, ...

External Resources: FuncBase

Expression

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000030407 (Evidence)
Entrez Gene	67369 (Evidence)
DFCI	TC1580807, TC1651729
NIA Mouse Gene Index	U028215
EC	2.3.2.5
Consensus CDS Project	CCDS20891.1
International Mouse Knockout Project Status	Qpctl

Sequences

Length	Strain/Species
genomic	67369	NCBI Gene Model | MGI Sequence Detail	8980	C57BL/6J
transcript	NM_026111	RefSeq | MGI Sequence Detail	2100	C57BL/6
polypeptide	Q8BH73	UniProt | EBI | MGI Sequence Detail	383	Not Applicable

All sequences(23) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(36 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007484	Peptidase M28
Protein Ontology	PR:000013566	glutaminyl-peptide cyclotransferase-like protein

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:176575 Alexandru A, et al., Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated A{beta} Is Induced by Pyroglutamate-A{beta} Formation. J Neurosci. 2011 Sep 7;31(36):12790-12801
All references(30)

Other accession IDs

MGI:2142285