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Saxo2 Gene Detail
Summary
  • Symbol
    Saxo2
  • Name
    stabilizer of axonemal microtubules 2
  • Synonyms
    1700129I04Rik, Fam154b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914618
    NCBI Gene: 330577
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:82632960-82648528 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 47.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914618
protein coding gene Chr7:82632960-82648565 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032444
protein coding gene Chr7:84763544-84780152 (-)
A/J MGP_AJ_G0032422
protein coding gene Chr7:82722886-82738453 (-)
AKR/J MGP_AKRJ_G0032358
protein coding gene Chr7:84595946-84611506 (-)
BALB/cJ MGP_BALBcJ_G0032434
protein coding gene Chr7:82387253-82403654 (-)
C3H/HeJ MGP_C3HHeJ_G0032148
protein coding gene Chr7:85171414-85186989 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032925
protein coding gene Chr7:88054384-88070847 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029935
protein coding gene Chr7:85157289-85172815 (-)
CAST/EiJ MGP_CASTEiJ_G0031475
protein coding gene Chr7:76139597-76156940 (-)
CBA/J MGP_CBAJ_G0032113
protein coding gene Chr7:90986927-91002502 (-)
DBA/2J MGP_DBA2J_G0032268
protein coding gene Chr7:81243663-81259112 (-)
FVB/NJ MGP_FVBNJ_G0032222
protein coding gene Chr7:81196580-81214442 (-)
LP/J MGP_LPJ_G0032349
protein coding gene Chr7:85973742-85989299 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032259
protein coding gene Chr7:91037377-91054914 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032945
protein coding gene Chr7:84008411-84025266 (-)
PWK/PhJ MGP_PWKPhJ_G0031195
protein coding gene Chr7:74463919-74479605 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031037
protein coding gene Chr7:70994625-71010171 (-)
WSB/EiJ MGP_WSBEiJ_G0031592
protein coding gene Chr7:84371344-84390402 (-)



Homology
more
  • Human Ortholog
    SAXO2, stabilizer of axonemal microtubules 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SAXO2, stabilizer of axonemal microtubules 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM154B
  • Links
    NCBI Gene ID: 283726
    neXtProt AC: NX_Q658L1
    UniProt: Q658L1

  • Chr Location
    15q25.2; chr15:82262811-82284927 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 25135
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SAXO2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038570 Ensembl Gene Model | MGI Sequence Detail 15569 C57BL/6J ±  kb
transcript ENSMUST00000056728 Ensembl | MGI Sequence Detail 2783 Not Applicable  
polypeptide ENSMUSP00000057993 Ensembl | MGI Sequence Detail 394 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory