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Paxbp1 Gene Detail
Summary
  • Symbol
    Paxbp1
  • Name
    PAX3 and PAX7 binding protein 1
  • Synonyms
    1810007M14Rik, Gcfc1, Pax3/7bp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914617
    NCBI Gene: 67367
  • Gene Overview
    MyGene.info: PAXBP1
Location & Maps
more
  • Sequence Map
    Chr16:91014037-91044543 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30507 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 52.30 cM, cytoband C3.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PAXBP1, PAX3 and PAX7 binding protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PAXBP1, PAX3 and PAX7 binding protein 1
    Orthology source: HomoloGene
  • Synonyms
    BM020, C21orf66, FSAP105, GCFC, GCFC1
  • Links
    NCBI Gene ID: 94104
    neXtProt AC: NX_Q9Y5B6

  • Chr Location
    21q21.3; chr21:32733899-32771858 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9604
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PAXBP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    14
  • Gene trapped
    5
  • Targeted
    9
  • Genomic Mutations
    6 involving Paxbp1
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016279 VEGA Gene Model | MGI Sequence Detail 30507 C57BL/6J ±  kb
transcript OTTMUST00000039069 VEGA | MGI Sequence Detail 3973 Not Applicable  
polypeptide OTTMUSP00000017451 VEGA | MGI Sequence Detail 919 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    336 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007890 PAX3- and PAX7-binding protein 1
  • InterPro Domains
    IPR012890 GC-rich sequence DNA-binding factor
    IPR022783 GC-rich sequence DNA-binding factor domain
Molecular
Reagents
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  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:189874 Diao Y, et al., Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Cell Stem Cell. 2012 Aug 3;11(2):231-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory