About   Help   FAQ
Loxhd1
Gene Detail
Symbol

Name
ID
Loxhd1
lipoxygenase homology domains 1
MGI:1914609
Synonyms
1700096C21Rik, sba
Feature Type
protein coding gene
Genetic Map
Chromosome 18
52.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr18:77307750-77442341 bp, + strand
From VEGA annotation of GRCm38

  134592 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Loxhd1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Chemically induced (ENU)(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice honozygous for an ENU-induced mutation exhibit hearing loss associated with hair cell and spiral ganglion degeneration.
 
Interactions
Loxhd1 interacts with 104 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process calcium ion transmembrane transport, detection of mechanical stimulus, ...
Component cell projection, membrane, ...
Function calcium channel activity
External Resources: FuncBase
Expression
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Other database
links
VEGA Gene Model OTTMUSG00000025866 (Evidence)
Ensembl Gene Model ENSMUSG00000032818 (Evidence)
Entrez Gene 240411 (Evidence)
UniGene 380247
DFCI TC1593805, TC1606795
DoTS DT.55159151, DT.94254105, DT.94256018
NIA Mouse Gene Index U018917
Consensus CDS Project CCDS50326.1
International Mouse Phenotyping Consortium Status Loxhd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025866 VEGA Gene Model | MGI Sequence Detail 134592 C57BL/6J ±  kb
transcript OTTMUST00000063742 VEGA | MGI Sequence Detail 4680 Not Applicable 
polypeptide OTTMUSP00000031564 VEGA | MGI Sequence Detail 1478 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(6)
Polymorphisms
SNPs within 2kb(989 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001024 PLAT/LH2 domain
Protein Ontology PR:000031082 lipoxygenase homology domain-containing protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193334 Xiong W, et al., TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells. Cell. 2012 Dec 7;151(6):1283-95
All references(22)
Other
accession IDs
MGI:3708146

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory