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1700093K21Rik Gene Detail
Summary
  • Symbol
    1700093K21Rik
  • Name
    RIKEN cDNA 1700093K21 gene
  • Synonyms
    b2b3025Clo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914608
    NCBI Gene: 67358
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:23516203-23521155 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4953 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 14.32 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    C2orf74, chromosome 2 open reading frame 74
  • Vertebrate Orthologs
    7
  • Human Ortholog
    C2orf74, chromosome 2 open reading frame 74
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 339804
    neXtProt AC: NX_A8MZ97
    UniProt: A8MZ97

  • Chr Location
    2p15; chr2:61145068-61164830 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with 1700093K21Rik mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 images
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele exhibit congenital heart defects associated with heterotaxy, as well as thoracic and abdominal visceral organ situs anomalies, and misaligned sternal vertebrae.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005280 VEGA Gene Model | MGI Sequence Detail 4953 C57BL/6J ±  kb
transcript OTTMUST00000011779 VEGA | MGI Sequence Detail 1030 Not Applicable  
polypeptide OTTMUSP00000005463 VEGA | MGI Sequence Detail 196 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    9 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR027813 Protein of unknown function DUF4642
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:5618822
References
more
  • Summaries
    All 21
    Diseases 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory