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Tmco5 Gene Detail
Summary
  • Symbol
    Tmco5
  • Name
    transmembrane and coiled-coil domains 5
  • Synonyms
    1700095F04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914606
    NCBI Gene: 67356
  • Gene Overview
    MyGene.info: TMCO5A
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:116878691-116892494 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.03 cM, cytoband E5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914606
protein coding gene Chr2:116878691-116892500 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026307
protein coding gene Chr2:119480304-119494045 (+)
A/J MGP_AJ_G0026268
protein coding gene Chr2:114633166-114646967 (+)
AKR/J MGP_AKRJ_G0026247
protein coding gene Chr2:117830922-117844693 (+)
BALB/cJ MGP_BALBcJ_G0026281
protein coding gene Chr2:114881563-114895270 (+)
C3H/HeJ MGP_C3HHeJ_G0026026
protein coding gene Chr2:118265932-118281896 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026728
protein coding gene Chr2:123418261-123432016 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024108
protein coding gene Chr2:109712076-109725891 (+)
CAST/EiJ MGP_CASTEiJ_G0025489
protein coding gene Chr2:118579493-118593270 (+)
CBA/J MGP_CBAJ_G0026003
protein coding gene Chr2:127772376-127786121 (+)
DBA/2J MGP_DBA2J_G0026142
protein coding gene Chr2:114063791-114079448 (+)
FVB/NJ MGP_FVBNJ_G0026104
protein coding gene Chr2:112895224-112908969 (+)
LP/J MGP_LPJ_G0026243
protein coding gene Chr2:119813137-119826898 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026123
protein coding gene Chr2:132194242-132208001 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026783
protein coding gene Chr2:117938113-117951866 (+)
PWK/PhJ MGP_PWKPhJ_G0025225
protein coding gene Chr2:113609134-113623176 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025024
protein coding gene Chr2:117073448-117087766 (+)
WSB/EiJ MGP_WSBEiJ_G0025558
protein coding gene Chr2:118768242-118781995 (+)



Homology
more
  • Human Ortholog
    TMCO5A, transmembrane and coiled-coil domains 5A
  • Vertebrate Orthologs
    5
  • Human Ortholog
    TMCO5A, transmembrane and coiled-coil domains 5A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TMCO5
  • Links
    NCBI Gene ID: 145942
    neXtProt AC: NX_Q8N6Q1
    UniProt: Q8N6Q1

  • Chr Location
    15q14; chr15:37934607-37997541 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027355 Ensembl Gene Model | MGI Sequence Detail 13804 C57BL/6J ±  kb
transcript ENSMUST00000028834 Ensembl | MGI Sequence Detail 1164 Not Applicable  
polypeptide ENSMUSP00000028834 Ensembl | MGI Sequence Detail 303 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031670 transmembrane and coiled-coil domain-containing protein 5A
  • InterPro Domains
    IPR026617 Transmembrane and coiled-coil domain-containing protein 2/5
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory