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Larp1b Gene Detail
Summary
  • Symbol
    Larp1b
  • Name
    La ribonucleoprotein 1B
  • Synonyms
    1700108L22Rik, 4933421B21Rik, Larp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914604
    NCBI Gene: 214048
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:40904263-40994669 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 19.61 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914604
protein coding gene Chr3:40904198-40994669 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027184
protein coding gene Chr3:38948889-39042579 (+)
A/J MGP_AJ_G0027144
protein coding gene Chr3:37997733-38087840 (+)
AKR/J MGP_AKRJ_G0027113
protein coding gene Chr3:38718127-38808508 (+)
BALB/cJ MGP_BALBcJ_G0027156
protein coding gene Chr3:37769176-37859637 (+)
C3H/HeJ MGP_C3HHeJ_G0026899
protein coding gene Chr3:38841370-38933821 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027602
protein coding gene Chr3:40567554-40658710 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024962
protein coding gene Chr3:35491763-35593158 (+)
CAST/EiJ MGP_CASTEiJ_G0026352
protein coding gene Chr3:38705064-38801307 (+)
CBA/J MGP_CBAJ_G0026876
protein coding gene Chr3:41716100-41811407 (+)
DBA/2J MGP_DBA2J_G0027010
protein coding gene Chr3:37462722-37554040 (+)
FVB/NJ MGP_FVBNJ_G0026978
protein coding gene Chr3:36835365-36925368 (+)
LP/J MGP_LPJ_G0027122
protein coding gene Chr3:39686131-39783612 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026996
protein coding gene Chr3:44178728-44273807 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027661
protein coding gene Chr3:38584478-38677522 (+)
PWK/PhJ MGP_PWKPhJ_G0026084
protein coding gene Chr3:37135608-37230352 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025897
protein coding gene Chr3:37977103-38073229 (+)
WSB/EiJ MGP_WSBEiJ_G0026426
protein coding gene Chr3:38593157-38683637 (+)



Homology
more
  • Human Ortholog
    LARP1B, La ribonucleoprotein 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LARP1B, La ribonucleoprotein 1B
  • Synonyms
    LARP2
  • Links
    NCBI Gene ID: 55132
    neXtProt AC: NX_Q659C4
    UniProt: Q659C4

  • Chr Location
    4q28.2; chr4:128060655-128222931 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025762 Ensembl Gene Model | MGI Sequence Detail 90407 C57BL/6J ±  kb
transcript ENSMUST00000048490 Ensembl | MGI Sequence Detail 2497 Not Applicable  
polypeptide ENSMUSP00000037127 Ensembl | MGI Sequence Detail 541 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR045180 La domain containing protein
    IPR006630 La-type HTH domain
    IPR006607 Protein of unknown function DM15
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
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  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1918324, MGI:2139606
References
more
  • Summaries
    All 32
    Diseases 1
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory