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Cstf1 Gene Detail
Summary
  • Symbol
    Cstf1
  • Name
    cleavage stimulation factor, 3' pre-RNA, subunit 1
  • Synonyms
    1700057K18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914587
    NCBI Gene: 67337
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172212601-172224368 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 94.84 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914587
protein coding gene Chr2:172212565-172224369 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026943
protein coding gene Chr2:178544469-178556222 (+)
A/J MGP_AJ_G0026910
protein coding gene Chr2:171064647-171077209 (+)
AKR/J MGP_AKRJ_G0026881
protein coding gene Chr2:176226128-176239734 (+)
BALB/cJ MGP_BALBcJ_G0026919
protein coding gene Chr2:171455386-171467123 (+)
C3H/HeJ MGP_C3HHeJ_G0026661
protein coding gene Chr2:176581188-176592962 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027366
protein coding gene Chr2:183702953-183714680 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024736
protein coding gene Chr2:164314870-164326264 (+)
CAST/EiJ MGP_CASTEiJ_G0026119
protein coding gene Chr2:177242769-177256678 (+)
CBA/J MGP_CBAJ_G0026638
protein coding gene Chr2:190559889-190571656 (+)
DBA/2J MGP_DBA2J_G0026776
protein coding gene Chr2:170160027-170171758 (+)
FVB/NJ MGP_FVBNJ_G0026742
protein coding gene Chr2:168756571-168768257 (+)
LP/J MGP_LPJ_G0026877
protein coding gene Chr2:178471667-178483386 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026761
protein coding gene Chr2:193547421-193559188 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027423
protein coding gene Chr2:176188072-176199839 (+)
PWK/PhJ MGP_PWKPhJ_G0025856
protein coding gene Chr2:169916314-169928252 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025656
protein coding gene Chr2:175191600-175203179 (+)
WSB/EiJ MGP_WSBEiJ_G0026192
protein coding gene Chr2:177165866-177177597 (+)



Homology
more
  • Human Ortholog
    CSTF1, cleavage stimulation factor subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSTF1, cleavage stimulation factor subunit 1
  • Synonyms
    CstF-50, CstFp50
  • Links
    NCBI Gene ID: 1477
    neXtProt AC: NX_Q05048
    UniProt: Q05048

  • Chr Location
    20q13.2-q13.31; chr20:56392371-56404526 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027498 Ensembl Gene Model | MGI Sequence Detail 11768 C57BL/6J ±  kb
transcript ENSMUST00000116375 Ensembl | MGI Sequence Detail 3451 Not Applicable  
polypeptide ENSMUSP00000112076 Ensembl | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005975 cleavage stimulation factor subunit 1
  • InterPro Domains
    IPR032028 Cleavage stimulation factor subunit 1, dimerisation domain
    IPR044633 Cleavage stimulation factor subunit 1-like
    IPR038184 CSTF1, dimerization domain superfamily
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
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  • All nucleic 76
    cDNA 76

    Microarray probesets 6
Other
Accession IDs
less
MGI:2139050
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory