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Atp8b3
Gene Detail
Symbol

Name
ID
Atp8b3
ATPase, class I, type 8B, member 3
MGI:1914581
Synonyms
1700042F02Rik, 1700056N23Rik, SAPLT
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:80519585-80539124 bp, - strand
From Ensembl annotation of GRCm38

  19540 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19034  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Atp8b3

Human
homologs
Human Homolog ATP8B3, ATPase, aminophospholipid transporter, class I, type 8B, member 3
NCBI Gene ID 148229
neXtProt AC  NX_O60423
Human Synonyms  ATPIK
Human Chr (Location)  19p13.3; chr19:1782075-1812276 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Litters sired by homozygous mutant mice are smaller than those sired by wild-type males. While sperm morphology and motility is intact in null sperm, fertilization rates are reduced due to impaired sperm-egg interactions.
 
Interactions
Atp8b3 interacts with 78 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ATP catabolic process, binding of sperm to zona pellucida, ...
Component acrosomal vesicle, cytoplasmic vesicle, ...
Function ATP binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 2
RT-PCR 15
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) cDNA(31) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000003341 (Evidence)
Entrez Gene67331 (Evidence)
UniGene52511
DFCITC1584988, TC1637691, TC1596874
DoTSDT.55280841, DT.101124593, DT.60105120
NIA Mouse Gene IndexU032012
EC3.6.3.1
Consensus CDS ProjectCCDS24024.1
International Mouse Knockout Project StatusAtp8b3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003341 Ensembl Gene Model | MGI Sequence Detail 19540 C57BL/6J ±  kb
transcript ENSMUST00000020383 Ensembl | MGI Sequence Detail 4411 Not Applicable 
polypeptide ENSMUSP00000020383 Ensembl | MGI Sequence Detail 1335 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(5) UniProt(7)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001757 Cation-transporting P-type ATPase
InterPro IPR023214 HAD-like domain
InterPro IPR006539 Phospholipid-transporting P-type ATPase, subfamily IV
InterPro IPR008250 P-type ATPase, A domain
InterPro IPR023299 P-type ATPase, cytoplasmic domain N
InterPro IPR018303 P-type ATPase, phosphorylation site
Protein Ontology PR:000029292 phospholipid-transporting ATPase IK
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:150226 Gong EY, et al., Expression of Atp8b3 in murine testis and its characterization as a testis specific P-type ATPase. Reproduction. 2009 Feb;137(2):345-51
All references(28)
Other
accession IDs
MGI:1915494

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory