About   Help   FAQ
Socs4 Gene Detail
Summary
  • Symbol
    Socs4
  • Name
    suppressor of cytokine signaling 4
  • Synonyms
    3110032M18Rik, A730004F22Rik, Socs7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914546
    NCBI Gene: 67296
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:47277143-47291591 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 24.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    108 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914546
protein coding gene Chr14:47276931-47296102 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021220
protein coding gene Chr14:41011979-41033082 (+)
A/J MGP_AJ_G0021167
protein coding gene Chr14:39773937-39793253 (+)
AKR/J MGP_AKRJ_G0021145
protein coding gene Chr14:41317304-41337675 (+)
BALB/cJ MGP_BALBcJ_G0021171
protein coding gene Chr14:39827301-39847229 (+)
C3H/HeJ MGP_C3HHeJ_G0020954
protein coding gene Chr14:41107890-41129580 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021605
protein coding gene Chr14:42759602-42780320 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019164
protein coding gene Chr14:39133378-39153409 (+)
CAST/EiJ MGP_CASTEiJ_G0020479
protein coding gene Chr14:38228736-38249516 (+)
CBA/J MGP_CBAJ_G0020920
protein coding gene Chr14:44112754-44138021 (+)
DBA/2J MGP_DBA2J_G0021043
protein coding gene Chr14:39667278-39686400 (+)
FVB/NJ MGP_FVBNJ_G0021028
protein coding gene Chr14:39408427-39427905 (+)
LP/J MGP_LPJ_G0021113
protein coding gene Chr14:41292924-41315514 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021053
protein coding gene Chr14:43475306-43495021 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021638
protein coding gene Chr14:40866266-40886098 (+)
PWK/PhJ MGP_PWKPhJ_G0020228
protein coding gene Chr14:36544311-36563593 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020052
protein coding gene Chr14:36990851-37010891 (+)
WSB/EiJ MGP_WSBEiJ_G0020535
protein coding gene Chr14:40963997-40984053 (+)



Homology
more
  • Human Ortholog
    SOCS4, suppressor of cytokine signaling 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SOCS4, suppressor of cytokine signaling 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SOCS7
  • Links
    NCBI Gene ID: 122809
    neXtProt AC: NX_Q8WXH5
    UniProt: Q8WXH5

  • Chr Location
    14q22.3; chr14:55027126-55049489 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67296 NCBI Gene Model | MGI Sequence Detail 14449 C57BL/6J ±  kb
transcript NM_080843 RefSeq | MGI Sequence Detail 2154 Not Specified  
polypeptide Q91ZA6 UniProt | EBI | MGI Sequence Detail 436 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 7
Other
Accession IDs
less
MGI:2145633, MGI:2145722, MGI:2145724
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:257927 Fairchild CL, et al., RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory