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Med31
Gene Detail
 Symbol
Name
ID
Med31
mediator complex subunit 31
MGI:1914529
Synonyms 3110004H13Rik, l11Jus15
Feature Type protein coding gene
Genetic Map
Chromosome 11
43.93 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:72211724-72215592 bp, - strand
From VEGA annotation of GRCm38

  3869 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9368  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Med31

Human
homologs
Human Homolog MED31, mediator complex subunit 31
NCBI Gene ID 51003
neXtProt AC  NX_Q9Y3C7
Human Synonyms  3110004H13Rik, Soh1
Human Chr (Location)  17p13.1; chr17:6643313-6651799 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Chemically induced (ENU)(1) Gene trapped(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit developmental delay, reduced cell proliferation, reduced ossification and chondrogenesis, and death during late-gestation.
 
Interactions
Med31 interacts with 57 markers (Mir25, Mir32, Mir96, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process limb development, negative regulation of fibroblast proliferation, ...
Component mediator complex, nucleus
Function protein binding, protein complex binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (96)    Tissues (95)    Images (1)
Theiler Stages: 22, 28
Assay TypeResults
RNA in situ 94
RT-PCR 2
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) cDNA(50) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006102 (Evidence)
Ensembl Gene ModelENSMUSG00000020801 (Evidence)
Entrez Gene67279 (Evidence)
UniGene159496
DFCITC1579807, TC1617012, TC1618784
Consensus CDS ProjectCCDS24981.1
International Mouse Knockout Project StatusMed31
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006102 VEGA Gene Model | MGI Sequence Detail 3869 C57BL/6J ±  kb
transcript OTTMUST00000013789 VEGA | MGI Sequence Detail 1161 Not Applicable 
polypeptide OTTMUSP00000006390 VEGA | MGI Sequence Detail 131 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(76 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008831 Mediator complex, subunit Med31
Protein Ontology PR:000010303 mediator of RNA polymerase II transcription subunit 31
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199738 Mauldin JP, et al., A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31. Curr Biol. 2013 Jan 21;23(2):162-7
All references(33)
Other
accession IDs
MGI:2671283

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory