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Myl12a Gene Detail
Summary
  • Symbol
    Myl12a
  • Name
    myosin, light chain 12A, regulatory, non-sarcomeric
  • Synonyms
    2900073G15Rik, brain specific myosin regulatory light chain, NMDA receptor-interacting protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914518
    NCBI Gene: 67268
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:71300788-71309528 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 41.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914518
 protein coding gene Chr17:71300651-71309873 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024003
 protein coding gene Chr17:73418813-73432137 (-)
A/J MGP_AJ_G0023961
 protein coding gene Chr17:71174674-71183810 (-)
AKR/J MGP_AKRJ_G0023930
 protein coding gene Chr17:72157203-72169014 (-)
BALB/cJ MGP_BALBcJ_G0023962
 protein coding gene Chr17:71101492-71110628 (-)
C3H/HeJ MGP_C3HHeJ_G0023726
 protein coding gene Chr17:73118693-73128512 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024408
 protein coding gene Chr17:76080207-76096811 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021853
 protein coding gene Chr17:66956236-66965587 (-)
CAST/EiJ MGP_CASTEiJ_G0023207
 protein coding gene Chr17:73532430-73547124 (-)
CBA/J MGP_CBAJ_G0023701
 protein coding gene Chr17:79268787-79277923 (-)
DBA/2J MGP_DBA2J_G0023830
 protein coding gene Chr17:69868028-69877163 (-)
FVB/NJ MGP_FVBNJ_G0023796
 protein coding gene Chr17:69333825-69342961 (-)
LP/J MGP_LPJ_G0023912
 protein coding gene Chr17:74174959-74185137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023824
 protein coding gene Chr17:79148201-79157337 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024452
 protein coding gene Chr17:72675166-72686797 (-)
PWK/PhJ MGP_PWKPhJ_G0022953
 protein coding gene Chr17:69164488-69173938 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022764
 protein coding gene Chr17:69385314-69399533 (-)
WSB/EiJ MGP_WSBEiJ_G0023274
 protein coding gene Chr17:73485662-73497252 (-)



Homology
more
  • Human Ortholog
    MYL12A, myosin light chain 12A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYL12A, myosin light chain 12A
  • Synonyms
    HEL-S-24, MLC-2B, MLCB, MRCL3, MRLC3, MYL2B
  • Links
    NCBI Gene ID: 10627
    neXtProt AC: NX_O14950, NX_P19105
    UniProt: P19105

  • Chr Location
    18p11.31; chr18:3247481-3256237 (+)  GRCh38
  • Human Ortholog
    MYL12B, myosin light chain 12B
  • Synonyms
    MLC-B, MRLC2
  • Links
    NCBI Gene ID: 103910
    neXtProt AC: NX_O14950
    UniProt: O14950

  • Chr Location
    18p11.31; chr18:3261479-3278461 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    18
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67268 NCBI Gene Model | MGI Sequence Detail 8741 C57BL/6J ±  kb
transcript NM_026064 RefSeq | MGI Sequence Detail 1779 C57BL/6  
polypeptide NP_001344749 RefSeq | MGI Sequence Detail 178 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146927, MGI:2147135
References
more
  • Summaries
    All 28
    Developmental Gene Expression 5
    Gene Ontology 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:334814 Tang YC, et al., Coordination of non-professional efferocytosis and actomyosin contractility during epithelial tissue morphogenesis. Cell Rep. 2023 Mar 28;42(3):112202
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory