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Zswim6 Gene Detail
Summary
  • Symbol
    Zswim6
  • Name
    zinc finger SWIM-type containing 6
  • Synonyms
    2900036G02Rik, mKIAA1577
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914513
    NCBI Gene: 67263
Location & Maps
more
  • Sequence Map
    Chr13:107724618-107890064 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      165447 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 59.39 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZSWIM6, zinc finger SWIM-type containing 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ZSWIM6, zinc finger SWIM-type containing 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AFND
  • Links
    NCBI Gene ID: 57688
    neXtProt AC: NX_Q9HCJ5

  • Chr Location
    5q12.1; chr5:61332273-61546172 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ZSWIM6 associations

Human Disease Mouse Models
       Acromelic Frontonasal Dysostosis; AFND   OMIM: 603671
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032846 Ensembl Gene Model | MGI Sequence Detail 165447 C57BL/6J ±  kb
transcript ENSMUST00000105097 Ensembl | MGI Sequence Detail 5456 Not Applicable  
polypeptide ENSMUSP00000100724 Ensembl | MGI Sequence Detail 1207 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    976 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032693 zinc finger SWIM domain-containing protein 6
  • InterPro Domains
    IPR007527 Zinc finger, SWIM-type
Molecular
Reagents
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  • All nucleic 34
    cDNA 34

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:230235 Smith JD, et al., Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis. Am J Hum Genet. 2014 Aug 7;95(2):235-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory