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Zfp422 Gene Detail
Summary
  • Symbol
    Zfp422
  • Name
    zinc finger protein 422
  • Synonyms
    2900028O21Rik, KOX15, Krox25, Krox-25-2, Krox26, Krox-26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914505
    NCBI Gene: 67255
  • Gene Overview
    MyGene.info: ZNF22
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:116624016-116628999 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 53.83 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    15
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914505
protein coding gene Chr6:116624016-116628999 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031173
protein coding gene Chr6:119309982-119315415 (-)
A/J MGP_AJ_G0031143
protein coding gene Chr6:114740078-114745057 (-)
AKR/J MGP_AKRJ_G0031073
protein coding gene Chr6:117820804-117824315 (-)
BALB/cJ MGP_BALBcJ_G0031153
protein coding gene Chr6:114536439-114541614 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0028776
protein coding gene Chr6:111744744-111749897 (-)
CAST/EiJ MGP_CASTEiJ_G0030260
protein coding gene Chr6:118205560-118211440 (-)
CBA/J MGP_CBAJ_G0023227
protein coding gene Chr17:35826713-35828458 (-)
DBA/2J MGP_DBA2J_G0030993
protein coding gene Chr6:113656486-113661030 (-)
FVB/NJ MGP_FVBNJ_G0030945
protein coding gene Chr6:112830678-112837068 (-)
LP/J MGP_LPJ_G0031071
protein coding gene Chr6:119337321-119345689 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030979
protein coding gene Chr6:131341537-131348833 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0029976
protein coding gene Chr6:112670635-112677014 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029804
protein coding gene Chr6:116597815-116601805 (-)
WSB/EiJ MGP_WSBEiJ_G0030343
protein coding gene Chr6:118130388-118135344 (-)



Homology
more
  • Human Ortholog
    ZNF22, zinc finger protein 22
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZNF22, zinc finger protein 22
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HKR-T1, KOX15, Zfp422, ZNF422
  • Links
    NCBI Gene ID: 7570
    neXtProt AC: NX_P17026
    UniProt: P17026

  • Chr Location
    10q11.21; chr10:45000825-45005329 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67255 NCBI Gene Model | MGI Sequence Detail 4984 C57BL/6J ±  kb
transcript NM_001302440 RefSeq | MGI Sequence Detail 3411 C57BL/6  
polypeptide Q9ERU3 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146997
References
more
  • Summaries
    All 39
    Developmental Gene Expression 8
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory