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L3hypdh
Gene Detail
Symbol

Name
ID
L3hypdh
L-3-hydroxyproline dehydratase (trans-)
MGI:1914467
Synonyms
2810055F11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
30.20 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:72073428-72085439 bp, - strand
From VEGA annotation of GRCm38

  12012 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12100  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: L3HYPDH
Protein SuperFamily: proline racemase
Gene Tree: L3hypdh

Human
homologs
L3HYPDH, L-3-hydroxyproline dehydratase (trans-)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 112849
neXtProt AC: NX_Q96EM0

Human Synonyms: C14orf149

Human Chr (Location): 14q23.1; chr14:59465511-59484438 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(5) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
L3hypdh interacts with 85 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process metabolic process
Component cellular_component
Function hydro-lyase activity, lyase activity, ...
External Resources: FuncBase
Expression
cDNA source data(23)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase l3hypdh    NEW 
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027641 (Evidence)
Ensembl Gene Model ENSMUSG00000019718 (Evidence)
Entrez Gene 67217 (Evidence)
UniGene 286120
DFCI TC1582406
DoTS DT.50315329, DT.91332906
NIA Mouse Gene Index U034053
EC 4.2.1.77
Consensus CDS Project CCDS25966.1
International Mouse Phenotyping Consortium Status L3hypdh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027641 VEGA Gene Model | MGI Sequence Detail 12012 C57BL/6J ±  kb
transcript OTTMUST00000068392 VEGA | MGI Sequence Detail 1831 Not Applicable 
polypeptide OTTMUSP00000034570 VEGA | MGI Sequence Detail 354 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(232 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008794 Proline racemase
Protein Ontology PR:000031435 trans-L-3-hydroxyproline dehydratase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187539 Visser WF, et al., Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. J Biol Chem. 2012 Jun 22;287(26):21654-62
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory