L3hypdh
Gene Detail

Symbol Name ID

L3hypdh L-3-hydroxyproline dehydratase (trans-) MGI:1914467

Synonyms

2810055F11Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 12

30.20 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr12:72073428-72085439 bp, - strand From VEGA annotation of GRCm38   12012 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:12100  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: proline racemase
Gene Tree: L3hypdh

Human homologs

Human Homolog		L3HYPDH, L-3-hydroxyproline dehydratase (trans-)
NCBI Gene ID		112849
neXtProt AC		NX_Q96EM0
Human Synonyms		C14orf149
Human Chr (Location)		14q23.1; chr14:59939406-59951073 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Targeted(2) Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	metabolic process
Component	cellular_component
Function	hydro-lyase activity, lyase activity, ...

External Resources: FuncBase

Expression

cDNA source data(23)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(24)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027641 (Evidence)
Ensembl Gene Model	ENSMUSG00000019718 (Evidence)
Entrez Gene	67217 (Evidence)
UniGene	286120
DFCI	TC1582406
DoTS	DT.50315329, DT.91332906
NIA Mouse Gene Index	U034053
EC	4.2.1.77
Consensus CDS Project	CCDS25966.1
International Mouse Knockout Project Status	L3hypdh

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027641	VEGA Gene Model | MGI Sequence Detail	12012	C57BL/6J
transcript	OTTMUST00000068392	VEGA | MGI Sequence Detail	1831	Not Applicable
polypeptide	OTTMUSP00000034570	VEGA | MGI Sequence Detail	354	Not Applicable

All sequences(23) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(110 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008794	Proline racemase
Protein Ontology	PR:000031435	trans-L-3-hydroxyproline dehydratase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187539 Visser WF, et al., Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. J Biol Chem. 2012 Jun 22;287(26):21654-62
All references(32)