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Mboat2 Gene Detail
Summary
  • Symbol
    Mboat2
  • Name
    membrane bound O-acyltransferase domain containing 2
  • Synonyms
    2810049G06Rik, Oact2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914466
    NCBI Gene: 67216
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:24831549-24964400 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 8.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1852 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914466
protein coding gene Chr12:24830879-24964400 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019633
protein coding gene Chr12:22520506-22652990 (+)
A/J MGP_AJ_G0019600
protein coding gene Chr12:21900809-22029763 (+)
AKR/J MGP_AKRJ_G0019571
protein coding gene Chr12:22636344-22767754 (+)
BALB/cJ MGP_BALBcJ_G0019577
protein coding gene Chr12:22167977-22299336 (+)
C3H/HeJ MGP_C3HHeJ_G0019381
protein coding gene Chr12:22520767-22655189 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020025
protein coding gene Chr12:23230684-23367803 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017649
protein coding gene Chr12:21381859-21509334 (+)
CAST/EiJ MGP_CASTEiJ_G0018936
protein coding gene Chr12:17490390-17631979 (+)
CBA/J MGP_CBAJ_G0019352
protein coding gene Chr12:23953586-24095477 (+)
DBA/2J MGP_DBA2J_G0019466
protein coding gene Chr12:21754215-21883857 (+)
FVB/NJ MGP_FVBNJ_G0019457
protein coding gene Chr12:21645098-21775261 (+)
LP/J MGP_LPJ_G0019536
protein coding gene Chr12:22586273-22723334 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019492
protein coding gene Chr12:23822190-23959147 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020064
protein coding gene Chr12:22209469-22342098 (+)
PWK/PhJ MGP_PWKPhJ_G0018703
protein coding gene Chr12:16494134-16627339 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018491
protein coding gene Chr12:16713693-16843837 (+)
WSB/EiJ MGP_WSBEiJ_G0018987
protein coding gene Chr12:22353332-22490112 (+)



Homology
more
  • Human Ortholog
    MBOAT2, membrane bound O-acyltransferase domain containing 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MBOAT2, membrane bound O-acyltransferase domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LPAAT, LPCAT4, LPEAT, LPLAT 2, OACT2
  • Links
    NCBI Gene ID: 129642
    neXtProt AC: NX_Q6ZWT7
    UniProt: Q6ZWT7

  • Chr Location
    2p25.1; chr2:8852690-9003750 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67216 NCBI Gene Model | MGI Sequence Detail 132852 C57BL/6J ±  kb
transcript NM_026037 RefSeq | MGI Sequence Detail 2802 C57BL/6  
polypeptide Q8R3I2 UniProt | EBI | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 50
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144960, MGI:2145040
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory