Ndufa13
Gene Detail

Symbol Name ID

Ndufa13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 MGI:1914434

Synonyms

2700054G14Rik, CDA016, CGI-39, Grim19, GRIM-19

Feature Type

protein coding gene

Genetic Map

Chromosome 8

34.03 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:69894188-69902558 bp, - strand From Ensembl annotation of GRCm38   8371 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41083  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Ndufa13

Human homologs

Human Homolog		NDUFA13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NCBI Gene ID		51079
neXtProt AC		NX_Q9P0J0
Human Synonyms		B16.6, CDA016, GRIM19, GRIM-19
Human Chr (Location)		19p13.2; chr19:19627019-19639013 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human NDUFA13

Alleles and phenotypes

All alleles(34) : Targeted(1) Gene trapped(33)
 

Homozygous null mice display embryonic lethality, failed gastrulation, absent organogenesis, small and abnormal inner cell mass and trophoblast, and abnormal mitochondria.

 

Gene Ontology (GO) classifications

All GO classifications: (26 annotations)

Process	apoptotic nuclear changes, apoptotic process, ...
Component	cytoplasm, integral to membrane, ...
Function	ATP binding, NADH dehydrogenase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (123)    Tissues (123)    Images (17)
Theiler Stages: 19, 21, 22, 23, 28

Assay Type	Results
Immunohistochemistry	2
RNA in situ	121

cDNA source data(162)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(162) cDNA(162)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000036199 (Evidence)
Entrez Gene	67184 (Evidence)
UniGene	21162
DFCI	TC1574130, TC1690822
NIA Mouse Gene Index	U048754
Consensus CDS Project	CCDS22353.1
International Mouse Knockout Project Status	Ndufa13

Sequences

Length	Strain/Species
genomic	ENSMUSG00000036199	Ensembl Gene Model | MGI Sequence Detail	8371	C57BL/6J
transcript	ENSMUST00000110167	Ensembl | MGI Sequence Detail	1243	Not Applicable
polypeptide	ENSMUSP00000105796	Ensembl | MGI Sequence Detail	144	Not Applicable

All sequences(24) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(54 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009346	GRIM-19
Protein Ontology	PR:000011071	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:188850 Chen Y, et al., Function of GRIM-19, a mitochondrial respiratory chain complex I protein, in innate immunity. J Biol Chem. 2012 Aug 3;287(32):27227-35
All references(40)

Other accession IDs

MGI:2142700