About   Help   FAQ
Ndufa13 Gene Detail
Summary
  • Symbol
    Ndufa13
  • Name
    NADH:ubiquinone oxidoreductase subunit A13
  • Synonyms
    2700054G14Rik, CDA016, CGI-39, Grim19, GRIM-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914434
    NCBI Gene: 67184
  • Gene Overview
    MyGene.info: NDUFA13
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:69894180-69902558 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.03 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914434
protein coding gene Chr8:69887788-69902558 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033682
protein coding gene Chr8:70123300-70131480 (-)
A/J MGP_AJ_G0033665
protein coding gene Chr8:67275417-67283922 (-)
AKR/J MGP_AKRJ_G0033590
protein coding gene Chr8:69181929-69190113 (-)
BALB/cJ MGP_BALBcJ_G0033661
protein coding gene Chr8:67501546-67510082 (-)
C3H/HeJ MGP_C3HHeJ_G0033371
protein coding gene Chr8:69843212-69851334 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034178
protein coding gene Chr8:72791280-72799664 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031122
protein coding gene Chr8:62099418-62108198 (-)
CAST/EiJ MGP_CASTEiJ_G0032696
protein coding gene Chr8:69307970-69316179 (-)
CBA/J MGP_CBAJ_G0033349
protein coding gene Chr8:75429210-75437355 (-)
DBA/2J MGP_DBA2J_G0033503
protein coding gene Chr8:67001737-67010315 (-)
FVB/NJ MGP_FVBNJ_G0033444
protein coding gene Chr8:66098368-66106966 (-)
LP/J MGP_LPJ_G0033590
protein coding gene Chr8:70173611-70181791 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033488
protein coding gene Chr8:78086449-78094828 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034196
protein coding gene Chr8:69363904-69372985 (-)
PWK/PhJ MGP_PWKPhJ_G0032404
protein coding gene Chr8:66286429-66294945 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032240
protein coding gene Chr8:68340165-68349722 (-)
WSB/EiJ MGP_WSBEiJ_G0032811
protein coding gene Chr8:69732838-69742025 (-)



Homology
more
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B16.6, CDA016, CGI-39, GRIM19, GRIM-19
  • Links
    NCBI Gene ID: 51079
    neXtProt AC: NX_Q9P0J0
    UniProt: Q9P0J0

  • Chr Location
    19p13.11; chr19:19516210-19528204 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human NDUFA13 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice display embryonic lethality, failed gastrulation, absent organogenesis, small and abnormal inner cell mass and trophoblast, and abnormal mitochondria.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036199 Ensembl Gene Model | MGI Sequence Detail 8379 C57BL/6J ±  kb
    transcript ENSMUST00000110167 Ensembl | MGI Sequence Detail 1251 Not Applicable  
    polypeptide ENSMUSP00000105796 Ensembl | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 163
      cDNA 163

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142700
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:257260 Hu H, et al., Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11908-11913

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory