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Ndufa13 Gene Detail
Summary
  • Symbol
    Ndufa13
  • Name
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
  • Synonyms
    2700054G14Rik, CDA016, CGI-39, Grim19, GRIM-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914434
    NCBI Gene: 67184
  • Gene Overview
    MyGene.info: NDUFA13
Location & Maps
more
  • Sequence Map
    Chr8:69894188-69902558 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8371 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.03 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B16.6, CDA016, CGI-39, GRIM19, GRIM-19
  • Links
    NCBI Gene ID: 51079
    neXtProt AC: NX_Q9P0J0

  • Chr Location
    19p13.2; chr19:19516210-19528204 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NDUFA13 associations

Human Disease Mouse Models
       Thyroid Carcinoma, Hurthle Cell   OMIM: 607464
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    35
  • Chemically induced (other)
    1
  • Gene trapped
    33
  • Targeted
    1
  • Genomic Mutations
    1 involving Ndufa13
  • Incidental Mutations
    APF
Homozygous null mice display embryonic lethality, failed gastrulation, absent organogenesis, small and abnormal inner cell mass and trophoblast, and abnormal mitochondria.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036199 Ensembl Gene Model | MGI Sequence Detail 8371 C57BL/6J ±  kb
transcript ENSMUST00000110167 Ensembl | MGI Sequence Detail 1243 Not Applicable  
polypeptide ENSMUSP00000105796 Ensembl | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    161 from dbSNP Build 142
Protein
Information
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  • Protein Ontology
    PR:000011071 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Molecular
Reagents
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  • All nucleic 162
    cDNA 162

    Microarray probesets 3
Other
Accession IDs
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MGI:2142700
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202910 Kalakonda S, et al., Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4213-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory