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Cdt1
Gene Detail
Symbol

Name
ID
Cdt1
chromatin licensing and DNA replication factor 1
MGI:1914427
Synonyms
2610318F11Rik, Ris2
Feature Type
protein coding gene
Genetic Map
Chromosome 8
71.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:122568015-122573128 bp, + strand
From Ensembl annotation of GRCm38

  5114 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32650  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cdt1

Human
homologs
Human Homolog CDT1, chromatin licensing and DNA replication factor 1
NCBI Gene ID 81620
neXtProt AC  NX_Q9H211
Human Synonyms  DUP, RIS2
Human Chr (Location)  16q24.3; chr16:88803778-88809258 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CDT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cdt1 interacts with 65 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell cycle, DNA replication, ...
Component nucleoplasm, nucleus
Function DNA binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (43)    Tissues (9)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 40
RT-PCR 3
cDNA source data(112)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(113) cDNA(112) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000006585 (Evidence)
Entrez Gene67177 (Evidence)
UniGene21873
DFCITC1718956, TC1597941, TC1572631, TC1595378
DoTSDT.94278451, DT.533047, DT.101278617
NIA Mouse Gene IndexU009914
PDB2KLO, 3A4C, 2RQQ, 2ZXX
Consensus CDS ProjectCCDS22741.1
International Mouse Knockout Project StatusCdt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006585 Ensembl Gene Model | MGI Sequence Detail 5114 C57BL/6J ±  kb
transcript ENSMUST00000006760 Ensembl | MGI Sequence Detail 2189 Not Applicable 
polypeptide ENSMUSP00000006760 Ensembl | MGI Sequence Detail 557 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014939 CDT1 Geminin-binding domain-like
Protein Ontology PR:000005293 DNA replication factor Cdt1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:170314 Albino D, et al., Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration. Int J Dev Biol. 2011;55(1):65-72
All references(41)
Other
accession IDs
MGI:2142800, MGI:2142842

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory