Cdt1
Gene Detail

Symbol Name ID

Cdt1 chromatin licensing and DNA replication factor 1 MGI:1914427

Synonyms

2610318F11Rik, Ris2

Feature Type

protein coding gene

Genetic Map

Chromosome 8

71.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:122568015-122573128 bp, + strand From Ensembl annotation of GRCm38   5114 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32650  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cdt1

Human homologs

Human Homolog		CDT1, chromatin licensing and DNA replication factor 1
NCBI Gene ID		81620
neXtProt AC		NX_Q9H211
Human Synonyms		DUP, RIS2
Human Chr (Location)		16q24.3; chr16:88870186-88875666 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CDT1

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	cell cycle, DNA replication, ...
Component	nucleus
Function	DNA binding, protein binding

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (43)    Tissues (9)    Images (24)
Theiler Stages: 13, 21, 22, 23, 28

Assay Type	Results
RNA in situ	40
RT-PCR	3

cDNA source data(111)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(112) cDNA(111) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000006585 (Evidence)
Entrez Gene	67177 (Evidence)
UniGene	21873
DFCI	TC1572631, TC1595378, TC1597941, TC1718956
DoTS	DT.101278617, DT.533047, DT.94278451
NIA Mouse Gene Index	U009914
PDB	2KLO, 2RQQ, 2ZXX, 3A4C
Consensus CDS Project	CCDS22741.1
International Mouse Knockout Project Status	Cdt1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000006585	Ensembl Gene Model | MGI Sequence Detail	5114	C57BL/6J
transcript	ENSMUST00000006760	Ensembl | MGI Sequence Detail	2189	Not Applicable
polypeptide	ENSMUSP00000006760	Ensembl | MGI Sequence Detail	557	Not Applicable

All sequences(45) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(28 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014939	CDT1 Geminin-binding domain-like
Protein Ontology	PR:000005293	DNA replication factor Cdt1
Protein Ontology	PR:000026970	DNA replication factor Cdt1 (mouse)

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:170314 Albino D, et al., Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration. Int J Dev Biol. 2011;55(1):65-72
All references(41)

Other accession IDs

MGI:2142800, MGI:2142842