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Lpar6 Gene Detail
Summary
  • Symbol
    Lpar6
  • Name
    lysophosphatidic acid receptor 6
  • Synonyms
    2610302I02Rik, P2ry5, P2y5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914418
    NCBI Gene: 67168
  • Gene Overview
    MyGene.info: LPAR6
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:73237891-73240358 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 38.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914418
protein coding gene Chr14:73237891-73243294 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021556
protein coding gene Chr14:67975401-67980795 (+)
A/J MGP_AJ_G0021515
protein coding gene Chr14:66489571-66494970 (+)
AKR/J MGP_AKRJ_G0021491
protein coding gene Chr14:68441454-68446857 (+)
BALB/cJ MGP_BALBcJ_G0021521
protein coding gene Chr14:66252971-66258370 (+)
C3H/HeJ MGP_C3HHeJ_G0021298
protein coding gene Chr14:68167126-68172533 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021962
protein coding gene Chr14:70968074-70973473 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019500
protein coding gene Chr14:64210444-64215775 (+)
CAST/EiJ MGP_CASTEiJ_G0020816
protein coding gene Chr14:64827212-64832573 (+)
CBA/J MGP_CBAJ_G0021266
protein coding gene Chr14:73196707-73202098 (+)
DBA/2J MGP_DBA2J_G0021389
protein coding gene Chr14:65873011-65878420 (+)
FVB/NJ MGP_FVBNJ_G0021367
protein coding gene Chr14:65253343-65258665 (+)
LP/J MGP_LPJ_G0021459
protein coding gene Chr14:69144120-69149465 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021396
protein coding gene Chr14:72026750-72033136 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021984
protein coding gene Chr14:67715683-67721082 (+)
PWK/PhJ MGP_PWKPhJ_G0020559
protein coding gene Chr14:62642150-62647495 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020394
protein coding gene Chr14:63683005-63688369 (+)
WSB/EiJ MGP_WSBEiJ_G0020869
protein coding gene Chr14:68066268-68072800 (+)



Homology
more
  • Human Ortholog
    LPAR6, lysophosphatidic acid receptor 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LPAR6, lysophosphatidic acid receptor 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARWH1, HYPT8, LAH3, P2RY5, P2Y5
  • Links
    NCBI Gene ID: 10161
    neXtProt AC: NX_P43657
    UniProt: P43657

  • Chr Location
    13q14.2; chr13:48411045-48444704 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human LPAR6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67168 NCBI Gene Model | MGI Sequence Detail 2468 C57BL/6J ±  kb
transcript NM_175116 RefSeq | MGI Sequence Detail 2468 C57BL/6  
polypeptide Q8BMC0 UniProt | EBI | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 55
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory