Lpar6
Gene Detail

Symbol Name ID

Lpar6 lysophosphatidic acid receptor 6 MGI:1914418

Synonyms

2610302I02Rik, P2ry5, P2y5

Feature Type

protein coding gene

Genetic Map

Chromosome 14

38.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:73237895-73243294 bp, + strand From VEGA annotation of GRCm38   5400 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55925  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: LPAR4-like receptor
Gene Tree: Lpar6

Human homologs

Human Homolog		LPAR6, lysophosphatidic acid receptor 6
NCBI Gene ID		10161
neXtProt AC		NX_P43657
Human Synonyms		ARWH1, LAH3, P2RY5, P2Y5
Human Chr (Location)		13q14; chr13:48411045-48444704 (-)  GRCh38
Disease Associations		(1) Diseases Associated with Human LPAR6

Mutations, alleles, and phenotypes

All mutations/alleles(16) : Gene trapped(10) Targeted(6)
Incidental mutations (data from APF )

Interactions

Lpar6 interacts with 166 markers (Mir1b, Mir17, Mir19a, ...)

View All

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	G-protein coupled receptor signaling pathway, signal transduction
Component	integral component of membrane, membrane, ...
Function	G-protein coupled receptor activity, signal transducer activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (2)    Tissues (2)   
Theiler Stages: 14, 15

Assay Type	Results
RT-PCR	2

cDNA source data(54)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular reagents

All nucleic(55) cDNA(54) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000036134 (Evidence)
Ensembl Gene Model	ENSMUSG00000033446 (Evidence)
Entrez Gene	67168 (Evidence)
UniGene	390681
DFCI	TC1578332
DoTS	DT.527426
NIA Mouse Gene Index	U015842
Consensus CDS Project	CCDS27268.1
International Mouse Knockout Project Status	Lpar6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036134	VEGA Gene Model | MGI Sequence Detail	5400	C57BL/6J
transcript	OTTMUST00000092880	VEGA | MGI Sequence Detail	5400	Not Applicable
polypeptide	OTTMUSP00000051426	VEGA | MGI Sequence Detail	344	Not Applicable

All sequences(25) RefSeq(2) UniProt(1)

Polymorphisms

SNPs within 2kb(89 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
InterPro	IPR000276	G protein-coupled receptor, rhodopsin-like
Protein Ontology	PR:000001632	oleoyl-L-alpha-lysophosphatidic acid receptor

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:196844 Furuta D, et al., Lysophosphatidic acid induces neurite branch formation through LPA3. Mol Cell Neurosci. 2012 May;50(1):21-34
All references(36)