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Arl8b Gene Detail
Summary
  • Symbol
    Arl8b
  • Name
    ADP-ribosylation factor-like 8B
  • Synonyms
    2610313E07Rik, 3100002J04Rik, Arl10c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914416
    NCBI Gene: 67166
  • Gene Overview
    MyGene.info: ARL8B
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr6:108783099-108825278 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42180 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 49.87 cM, cytoband E2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARL8B, ADP ribosylation factor like GTPase 8B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARL8B, ADP ribosylation factor like GTPase 8B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARL10C, Gie1
  • Links
    NCBI Gene ID: 55207
    neXtProt AC: NX_Q9NVJ2
    UniProt: Q9NVJ2

  • Chr Location
    3p26.1; chr3:5122245-5180916 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 3 alleles in 3 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display perinatal lethality with impaired visceral yolk sac function and reduced embryo size.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000056447 VEGA Gene Model | MGI Sequence Detail 42180 C57BL/6J ±  kb
    transcript OTTMUST00000139446 VEGA | MGI Sequence Detail 4443 Not Applicable  
    polypeptide OTTMUSP00000073163 VEGA | MGI Sequence Detail 186 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      369 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 23

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916525
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:256313 Saitoh SI, et al., TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells. Nat Commun. 2017 Nov 17;8(1):1592

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory