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Arl8b Gene Detail
Summary
  • Symbol
    Arl8b
  • Name
    ADP-ribosylation factor-like 8B
  • Synonyms
    2610313E07Rik, 3100002J04Rik, Arl10c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914416
    NCBI Gene: 67166
  • Gene Overview
    MyGene.info: ARL8B
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:108783059-108823723 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 49.87 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914416
protein coding gene Chr6:108783059-108825278 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031102
protein coding gene Chr6:111070655-111113741 (+)
A/J MGP_AJ_G0031071
protein coding gene Chr6:106862564-106908643 (+)
AKR/J MGP_AKRJ_G0031002
protein coding gene Chr6:109743691-109787957 (+)
BALB/cJ MGP_BALBcJ_G0031082
protein coding gene Chr6:106790585-106833051 (+)
C3H/HeJ MGP_C3HHeJ_G0030626
protein coding gene Chr6:74571608-74613079 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031541
protein coding gene Chr6:113987198-114029388 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028705
protein coding gene Chr6:104148110-104191593 (+)
CAST/EiJ MGP_CASTEiJ_G0030189
protein coding gene Chr6:110124112-110172985 (+)
CBA/J MGP_CBAJ_G0030768
protein coding gene Chr6:118387383-118432117 (+)
DBA/2J MGP_DBA2J_G0030921
protein coding gene Chr6:105995385-106041800 (+)
FVB/NJ MGP_FVBNJ_G0030875
protein coding gene Chr6:105029457-105069934 (+)
LP/J MGP_LPJ_G0031001
protein coding gene Chr6:111127362-111170860 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030909
protein coding gene Chr6:122590759-122634136 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031568
protein coding gene Chr6:109691181-109735068 (+)
PWK/PhJ MGP_PWKPhJ_G0029905
protein coding gene Chr6:104934652-104975216 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029733
protein coding gene Chr6:108474692-108515000 (+)
WSB/EiJ MGP_WSBEiJ_G0030273
protein coding gene Chr6:110220333-110264323 (+)



Homology
more
  • Human Ortholog
    ARL8B, ADP ribosylation factor like GTPase 8B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARL8B, ADP ribosylation factor like GTPase 8B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARL10C, Gie1
  • Links
    NCBI Gene ID: 55207
    neXtProt AC: NX_Q9NVJ2
    UniProt: Q9NVJ2

  • Chr Location
    3p26.1; chr3:5122245-5180916 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 3 alleles in 3 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display perinatal lethality with impaired visceral yolk sac function and reduced embryo size.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67166 NCBI Gene Model | MGI Sequence Detail 40665 C57BL/6J ±  kb
    transcript NM_026011 RefSeq | MGI Sequence Detail 2928 C57BL/6  
    polypeptide Q9CQW2 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 24

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916525
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:256313 Saitoh SI, et al., TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells. Nat Commun. 2017 Nov 17;8(1):1592

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory