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Lipt2 Gene Detail
Summary
  • Symbol
    Lipt2
  • Name
    lipoyl(octanoyl) transferase 2 (putative)
  • Synonyms
    2610209A20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914414
    NCBI Gene: 67164
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:99808484-99810138 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.33 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914414
 protein coding gene Chr7:99808484-99810572 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032563
 protein coding gene Chr7:103023170-103025195 (+)
A/J MGP_AJ_G0032537
 protein coding gene Chr7:100439644-100441669 (+)
AKR/J MGP_AKRJ_G0032473
 protein coding gene Chr7:102824314-102826339 (+)
BALB/cJ MGP_BALBcJ_G0032548
 protein coding gene Chr7:100110928-100112953 (+)
C3H/HeJ MGP_C3HHeJ_G0032263
 protein coding gene Chr7:103193176-103195191 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033046
 protein coding gene Chr7:106942478-106944566 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030040
 protein coding gene Chr7:102842835-102844823 (+)
CAST/EiJ MGP_CASTEiJ_G0031590
 protein coding gene Chr7:94737556-94739582 (+)
CBA/J MGP_CBAJ_G0032230
 protein coding gene Chr7:110628141-110630156 (+)
DBA/2J MGP_DBA2J_G0032381
 protein coding gene Chr7:98768917-98770932 (+)
FVB/NJ MGP_FVBNJ_G0032338
 protein coding gene Chr7:98560049-98562074 (+)
LP/J MGP_LPJ_G0032471
 protein coding gene Chr7:104380780-104382805 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032371
 protein coding gene Chr7:112037169-112039257 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033068
 protein coding gene Chr7:102094342-102096430 (+)
PWK/PhJ MGP_PWKPhJ_G0031308
 protein coding gene Chr7:91872454-91874470 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031151
 protein coding gene Chr7:89402186-89404178 (+)
WSB/EiJ MGP_WSBEiJ_G0031707
 protein coding gene Chr7:102788648-102790736 (+)



Homology
more
  • Human Ortholog
    LIPT2, lipoyl(octanoyl) transferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LIPT2, lipoyl(octanoyl) transferase 2
  • Links
    NCBI Gene ID: 387787
    neXtProt AC: NX_A6NK58
    UniProt: A6NK58

  • Chr Location
    11q13.4; chr11:74490519-74493724 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Lipt2
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    20
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67164 NCBI Gene Model | MGI Sequence Detail 1655 C57BL/6J ±  kb
transcript NM_026010 RefSeq | MGI Sequence Detail 1235 C57BL/6  
polypeptide Q9D009 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000030327 octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
    (term hierarchy)
  • EC
    2.3.1.181
  • InterPro Domains
    IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain
    IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
    IPR000544 Octanoyltransferase
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:340654 Cao X, et al., Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7063-E7072
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory