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Lipt2 Gene Detail
Summary
  • Symbol
    Lipt2
  • Name
    lipoyl(octanoyl) transferase 2 (putative)
  • Synonyms
    2610209A20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914414
    NCBI Gene: 67164
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:99808484-99810138 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.33 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914414
 protein coding gene Chr7:99808484-99810572 (+)
129S1/SvImJ ENSMUSG00200047733
 protein coding gene Chr7:86637353-86639378 (+)
A/J ENSMUSG00195036108
 protein coding gene Chr7:91142769-91144794 (+)
AKR/J ENSMUSG00220049587
 protein coding gene Chr7:84559409-84561434 (+)
BALB/cJ ENSMUSG00180027063
 protein coding gene Chr7:87815785-87817810 (+)
C3H/HeJ ENSMUSG00175022629
 protein coding gene Chr7:88465467-88467482 (+)
C57BL/6NJ ENSMUSG00215015107
 protein coding gene Chr7:87654642-87656730 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030040
 protein coding gene Chr7:102842835-102844823 (+)
CAST/EiJ ENSTCUG00005052537
 protein coding gene Chr7:91058699-91060725 (+)
CBA/J ENSMUSG00210024316
 protein coding gene Chr7:88319176-88321191 (+)
DBA/2J ENSMUSG00185056645
 protein coding gene Chr7:92640575-92642590 (+)
FVB/NJ ENSMUSG00205019527
 protein coding gene Chr7:88313912-88315937 (+)
JF1/MsJ ENSUMUG00000046321
 protein coding gene Chr7:97545553-97547568 (+)
LP/J ENSMUSG00230039538
 protein coding gene Chr7:98779124-98781149 (+)
NOD/ShiLtJ ENSMUSG00190017740
 protein coding gene Chr7:88587522-88589610 (+)
NZO/HlLtJ ENSMUSG00225049730
 protein coding gene Chr7:96956881-96958969 (+)
PWK/PhJ ENSLUMG00010038825
 protein coding gene Chr7:86783334-86785350 (+)
SPRET/EiJ ENSMSPG00010011992
 protein coding gene Chr7:88025626-88027108 (+)
WSB/EiJ ENSIUOG00005009114
 protein coding gene Chr7:88941479-88943567 (+)



Homology
more
  • Human Ortholog
    LIPT2, lipoyl(octanoyl) transferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LIPT2, lipoyl(octanoyl) transferase 2
  • Links
    NCBI Gene ID: 387787
    UniProt: A6NK58

  • Chr Location
    11q13.4; chr11:74490519-74493724 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    20
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67164 NCBI Gene Model | MGI Sequence Detail 1655 C57BL/6J ±  kb
    transcript NM_026010 RefSeq | MGI Sequence Detail 1235 C57BL/6  
    polypeptide Q9D009 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000030327 octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
      (term hierarchy)
    • EC
      2.3.1.181
    • InterPro Domains
      IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain
      IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
      IPR000544 Octanoyltransferase
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 21

      Microarray probesets 3
    References
    more
    • Summaries
      All 46
      Gene Ontology 13
      Phenotypes 14
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:340654 Cao X, et al., Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7063-E7072
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory