About   Help   FAQ
Ccdc47
Gene Detail
Symbol

Name
ID
Ccdc47
coiled-coil domain containing 47
MGI:1914413
Synonyms
2610204L23Rik, asp4, calumin
Feature Type
protein coding gene
Genetic Map
Chromosome 11
68.89 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:106197408-106216344 bp, - strand
From VEGA annotation of GRCm38

  18937 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41351  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ccdc47

Human
homologs
Human Homolog CCDC47, coiled-coil domain containing 47
NCBI Gene ID 57003
neXtProt AC  NX_Q96A33
Human Synonyms  MSTP041
Human Chr (Location)  17q23.3; chr17:63745250-63773728 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(18) : Gene trapped(15) Targeted(3)
Incidental mutations (data from APF )
 
More than half of homozygous null mice die at early embryonic stages while the rest die shortly after birth. Mouse embryonic fibroblasts display insufficient Ca2+ contents in intracellular stores, impaired store-operated Ca2+ entry, and enhanced endoplasmic reticulum stress-induced apoptosis.
 
Interactions
Ccdc47 interacts with 390 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process calcium ion homeostasis, embryo development, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function calcium ion binding, poly(A) RNA binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (24)    Tissues (11)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
cDNA source data(176)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(177) cDNA(177)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000003221 (Evidence)
Ensembl Gene ModelENSMUSG00000078622 (Evidence)
Entrez Gene67163 (Evidence)
UniGene22109
DFCITC1680499, TC1575368
NIA Mouse Gene IndexU270058
Consensus CDS ProjectCCDS25551.1
International Mouse Knockout Project StatusCcdc47
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003221 VEGA Gene Model | MGI Sequence Detail 18937 C57BL/6J ±  kb
transcript OTTMUST00000006685 VEGA | MGI Sequence Detail 5193 Not Applicable 
polypeptide OTTMUSP00000003177 VEGA | MGI Sequence Detail 483 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012879 Protein of unknown function DUF1682
Protein Ontology PR:000031282 coiled-coil domain-containing protein 47
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory