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Nkain1 Gene Detail
Summary
  • Symbol
    Nkain1
  • Name
    Na+/K+ transporting ATPase interacting 1
  • Synonyms
    2610200G18Rik, 2810426C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914399
    NCBI Gene: 67149
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:130531602-130574173 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.43 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    337 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914399
protein coding gene Chr4:130530131-130574173 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028852
protein coding gene Chr4:132549853-132594642 (-)
A/J MGP_AJ_G0028811
protein coding gene Chr4:127098551-127140817 (+)
AKR/J MGP_AKRJ_G0028764
protein coding gene Chr4:130662593-130709327 (+)
BALB/cJ MGP_BALBcJ_G0028834
protein coding gene Chr4:127710734-127754202 (+)
C3H/HeJ MGP_C3HHeJ_G0028548
protein coding gene Chr4:130849770-130893908 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029276
protein coding gene Chr4:137371498-137416807 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026548
protein coding gene Chr4:120210950-120253174 (+)
CAST/EiJ MGP_CASTEiJ_G0027981
protein coding gene Chr4:128931336-128976320 (+)
CBA/J MGP_CBAJ_G0028514
protein coding gene Chr4:140870986-140919055 (+)
DBA/2J MGP_DBA2J_G0028663
protein coding gene Chr4:127531121-127573279 (+)
FVB/NJ MGP_FVBNJ_G0028630
protein coding gene Chr4:126329427-126382311 (+)
LP/J MGP_LPJ_G0028764
protein coding gene Chr4:132736693-132780135 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028656
protein coding gene Chr4:145565750-145611084 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029314
protein coding gene Chr4:131030864-131077525 (+)
PWK/PhJ MGP_PWKPhJ_G0027702
protein coding gene Chr4:124160227-124220917 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027528
protein coding gene Chr4:126897214-126940996 (+)
WSB/EiJ MGP_WSBEiJ_G0028061
protein coding gene Chr4:131178949-131225400 (+)



Homology
more
  • Human Ortholog
    NKAIN1, sodium/potassium transporting ATPase interacting 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NKAIN1, sodium/potassium transporting ATPase interacting 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM77C
  • Links
    NCBI Gene ID: 79570
    neXtProt AC: NX_Q4KMZ8
    UniProt: Q4KMZ8

  • Chr Location
    1p35.2; chr1:31179270-31239887 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11566
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NKAIN1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Nkain1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078532 Ensembl Gene Model | MGI Sequence Detail 42572 C57BL/6J ±  kb
transcript ENSMUST00000105993 Ensembl | MGI Sequence Detail 1202 Not Applicable  
polypeptide ENSMUSP00000101614 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000011226 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
  • InterPro Domains
    IPR008516 Na,K-Atpase Interacting protein
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 8
Other
Accession IDs
less
MGI:1919996
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:243411 Rutledge EA, et al., Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory