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Ikzf5 Gene Detail
Summary
  • Symbol
    Ikzf5
  • Name
    IKAROS family zinc finger 5
  • Synonyms
    2610034F18Rik, Zfpn1a5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914393
    NCBI Gene: 67143
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:131388649-131410506 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 73.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914393
protein coding gene Chr7:131388649-131410521 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033104
protein coding gene Chr7:136015240-136036757 (-)
A/J MGP_AJ_G0033086
protein coding gene Chr7:132301869-132328932 (-)
AKR/J MGP_AKRJ_G0033018
protein coding gene Chr7:135806635-135833039 (-)
BALB/cJ MGP_BALBcJ_G0033087
protein coding gene Chr7:131986714-132011498 (-)
C3H/HeJ MGP_C3HHeJ_G0032801
protein coding gene Chr7:135663355-135686657 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033598
protein coding gene Chr7:141203839-141231050 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030569
protein coding gene Chr7:133572319-133594341 (-)
CAST/EiJ MGP_CASTEiJ_G0032131
protein coding gene Chr7:127511112-127536439 (-)
CBA/J MGP_CBAJ_G0032774
protein coding gene Chr7:146099921-146116895 (-)
DBA/2J MGP_DBA2J_G0032926
protein coding gene Chr7:130281124-130303588 (-)
FVB/NJ MGP_FVBNJ_G0032879
protein coding gene Chr7:130147385-130169007 (-)
LP/J MGP_LPJ_G0033020
protein coding gene Chr7:137506923-137530773 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032911
protein coding gene Chr7:147017629-147040838 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033618
protein coding gene Chr7:134802120-134824025 (-)
PWK/PhJ MGP_PWKPhJ_G0031837
protein coding gene Chr7:123315453-123336799 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031683
protein coding gene Chr7:121575185-121598017 (-)
WSB/EiJ MGP_WSBEiJ_G0032242
protein coding gene Chr7:135701679-135726930 (-)



Homology
more
  • Human Ortholog
    IKZF5, IKAROS family zinc finger 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IKZF5, IKAROS family zinc finger 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PEGASUS, ZNFN1A5
  • Links
    NCBI Gene ID: 64376
    neXtProt AC: NX_Q9H5V7
    UniProt: Q9H5V7

  • Chr Location
    10q26.13; chr10:122990806-123008850 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 23363
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IKZF5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67143 NCBI Gene Model | MGI Sequence Detail 21858 C57BL/6J ±  kb
transcript NM_175115 RefSeq | MGI Sequence Detail 4440 C57BL/6  
polypeptide Q8BU00 UniProt | EBI | MGI Sequence Detail 419 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 57
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 37
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:262823 Kasowitz SD, et al., Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018 May;14(5):e1007412

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory