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Fbxo5
Gene Detail
 Symbol
Name
ID
Fbxo5
F-box protein 5
MGI:1914391
Synonyms 2510044I10Rik, Emi1, Fbxo31
Feature Type protein coding gene
Genetic Map
Chromosome 10
1.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:5799160-5805600 bp, - strand
From VEGA annotation of GRCm38

  6441 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8135  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fbxo5

Human
homologs
Human Homolog FBXO5, F-box protein 5
NCBI Gene ID 26271
neXtProt AC  NX_Q9UKT4
Human Synonyms  EMI1, FBX5, Fbxo31
Human Chr (Location)  6q25.2; chr6:152970523-152983605 (-)  GRCh38
Alleles
and
phenotypes
All alleles(47) : Gene trapped(43) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display embryonic lethality before implantation, impaired embryogenesis, and mitotic abnormalities.
 
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cell cycle, cell division, ...
Component cytoplasm, cytoskeleton, ...
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (80)    Tissues (27)    Images (23)
Theiler Stages: 1, 2, 3, 5, 11, 13, 23, 28
Assay TypeResults
RNA in situ 50
Western blot 10
RT-PCR 20
cDNA source data(45)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(47) cDNA(45) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000022756 (Evidence)
Ensembl Gene ModelENSMUSG00000019773 (Evidence)
Entrez Gene67141 (Evidence)
UniGene197520
DoTSDT.91342067, DT.97408276
NIA Mouse Gene IndexU031497
Consensus CDS ProjectCCDS56683.1
International Mouse Knockout Project StatusFbxo5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022756 VEGA Gene Model | MGI Sequence Detail 6441 C57BL/6J ±  kb
transcript OTTMUST00000054631 VEGA | MGI Sequence Detail 1940 Not Applicable 
polypeptide OTTMUSP00000026092 VEGA | MGI Sequence Detail 421 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001810 F-box domain, cyclin-like
Protein Ontology PR:000007417 F-box only protein 5
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Other
accession IDs
MGI:2143939

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory