About   Help   FAQ
Kbtbd4 Gene Detail
Summary
  • Symbol
    Kbtbd4
  • Name
    kelch repeat and BTB (POZ) domain containing 4
  • Synonyms
    2510026C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914386
    NCBI Gene: 67136
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90735113-90740905 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.44 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914386
 protein coding gene Chr2:90735084-90741970 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026136
 protein coding gene Chr2:92191666-92198516 (+)
A/J MGP_AJ_G0026097
 protein coding gene Chr2:88511162-88518054 (+)
AKR/J MGP_AKRJ_G0026078
 protein coding gene Chr2:90960929-90967790 (+)
BALB/cJ MGP_BALBcJ_G0026106
 protein coding gene Chr2:88673632-88680507 (+)
C3H/HeJ MGP_C3HHeJ_G0025857
 protein coding gene Chr2:91236865-91243707 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026557
 protein coding gene Chr2:95452070-95460353 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023948
 protein coding gene Chr2:85029452-85036145 (+)
CAST/EiJ MGP_CASTEiJ_G0025322
 protein coding gene Chr2:91756560-91763421 (+)
CBA/J MGP_CBAJ_G0025835
 protein coding gene Chr2:98688495-98695372 (+)
DBA/2J MGP_DBA2J_G0025971
 protein coding gene Chr2:88109097-88115944 (+)
FVB/NJ MGP_FVBNJ_G0025934
 protein coding gene Chr2:87215884-87222755 (+)
LP/J MGP_LPJ_G0026075
 protein coding gene Chr2:92406140-92412939 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025960
 protein coding gene Chr2:101739359-101746291 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026611
 protein coding gene Chr2:91013974-91022022 (+)
PWK/PhJ MGP_PWKPhJ_G0025057
 protein coding gene Chr2:87832979-87839899 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024858
 protein coding gene Chr2:90595811-90602637 (+)
WSB/EiJ MGP_WSBEiJ_G0025389
 protein coding gene Chr2:91603893-91611854 (+)



Homology
more
  • Human Ortholog
    KBTBD4, kelch repeat and BTB domain containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KBTBD4, kelch repeat and BTB domain containing 4
  • Synonyms
    BKLHD4, HSPC252
  • Links
    NCBI Gene ID: 55709
    UniProt: Q9NVX7

  • Chr Location
    11p11.2; chr11:47572197-47578976 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    847
  • Tissues
    64
  • cDNA Data
    65
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67136 NCBI Gene Model | MGI Sequence Detail 5793 C57BL/6J ±  kb
transcript NM_025991 RefSeq | MGI Sequence Detail 2411 C57BL/6  
polypeptide Q8R179 UniProt | EBI | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 65

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5:e16087
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory